The challenge of equipoise in trials with a surgical and non-surgical comparison: a qualitative synthesis using meta-ethnography

L Davies, D Beard, JA Cook, A Price, I Osbeck, F Toye - Trials, 2021 - Springer
Background Randomised controlled trials in surgery can be a challenge to design and
conduct, especially when including a non-surgical comparison. As few as half of initiated …

A call for structured ethics appendices in social science papers

E Asiedu, D Karlan… - Proceedings of the …, 2021 - National Acad Sciences
Ethics in social science experimentation and data collection are often discussed but rarely
articulated in writing as part of research outputs. Although papers typically reference human …

Randomised controlled trial to establish the clinical and cost-effectiveness of expectant management versus preoperative imaging with magnetic resonance …

M Clout, J Blazeby, C Rogers, B Reeves, M Lazaroo… - BMJ open, 2021 - bmjopen.bmj.com
Introduction Surgery to remove the gallbladder (laparoscopic cholecystectomy (LC)) is the
standard treatment for symptomatic gallbladder disease. One potential complication of …

[HTML][HTML] Conservative treatment for uncomplicated appendicitis in children: the CONTRACT feasibility study, including feasibility RCT.

NJ Hall, FC Sherratt, S Eaton, I Reading… - Health Technology …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Although non-operative treatment is known to be effective for the treatment
of uncomplicated acute appendicitis in children, randomised trial data comparing important …

Maximising recruitment to a randomised controlled trial for chronic rhinosinusitis using qualitative research methods: the MACRO conversation study

C McDermott, J Vennik, C Philpott, S Le Conte… - Trials, 2021 - Springer
Abstract Background Randomised controlled trials (RCTs) are considered the 'gold
standard'of medical evidence; however, recruitment can be challenging. The MACRO trial is …

Conservative treatment of appendicitis in children: the CONTRACT feasibility randomised controlled trial and mixed methods study

N Hall, S Eaton, F Sherratt, I Reading… - Health Technology …, 2021 - discovery.ucl.ac.uk
BACKGROUND: Although non-operative treatment is known to be effective for the treatment
of uncomplicated acute appendicitis in children, randomised trial data comparing important …