Antigen presentation, autoantibody production, and therapeutic targets in autoimmune liver disease

AK Horst, KG Kumashie, K Neumann, L Diehl… - Cellular & molecular …, 2021 - nature.com
The liver is an important immunological organ that controls systemic tolerance. The liver
harbors professional and unconventional antigen-presenting cells that are crucial for …

Tofacitinib inhibits inflammatory cytokines from ulcerative colitis and healthy mucosal explants and is associated with pSTAT1/3 reduction in T-cells

RM Brand, BA Moore, A Zyhowski… - American Journal …, 2021 - journals.physiology.org
Poor translatability of animal disease models has hampered the development of new
inflammatory bowel disorder (IBD) therapeutics. We describe a preclinical, ex vivo system …

[HTML][HTML] Translational Human Pathophysiology: Tofacitinib inhibits inflammatory cytokines from ulcerative colitis and healthy mucosal explants and is associated with …

RM Brand, BA Moore, A Zyhowski… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Poor translatability of animal disease models has hampered the development of new
inflammatory bowel disorder (IBD) therapeutics. We describe a preclinical, ex vivo system …

Investigating Determinants of Immunogenicity and Safety in Zika Live Attenuated Vaccines

YCH Tin - 2021 - search.proquest.com
Zika virus (ZIKV) emerged into prominence during the 2016 outbreak in the Americas, where
its association with fetal demise and malformations ignited global health concern. In …