[HTML][HTML] Cerebral small vessel disease: A review

J Chojdak-Łukasiewicz, E Dziadkowiak… - … in Clinical and …, 2021 - advances.umw.edu.pl
Cerebral small vessel disease (CSVD) is the most common, chronic and progressive
vascular disease. The changes affect arterioles, capillaries and small veins supplying the …

[HTML][HTML] Risk factors of cerebral small vessel disease: A systematic review and meta-analysis

Z Wang, Q Chen, J Chen, N Yang, K Zheng - Medicine, 2021 - journals.lww.com
Background: Cerebral small vessel disease (CSVD) is a common neurological disease
under the effect of multiple factors. Although some literature analyzes and summarizes the …

Low plasma ergothioneine levels are associated with neurodegeneration and cerebrovascular disease in dementia

LY Wu, IK Cheah, JR Chong, YL Chai, JY Tan… - Free Radical Biology …, 2021 - Elsevier
Ergothioneine (ET) is a dietary amino-thione with strong antioxidant and cytoprotective
properties and has possible therapeutic potential for neurodegenerative and vascular …

A geroscience motivated approach to treat Alzheimer's disease: senolytics move to clinical trials

MM Gonzales, S Krishnamurthy, V Garbarino… - Mechanisms of ageing …, 2021 - Elsevier
The pathogenic processes driving Alzheimer's disease (AD) are complex. An incomplete
understanding of underlying disease mechanisms has presented insurmountable obstacles …

[HTML][HTML] High burden of cerebral white matter lesion in 9 Asian cities

BYK Lam, B Yiu, E Ampil, CLH Chen, Y Dikot… - Scientific Reports, 2021 - nature.com
Age-related white matter lesion (WML) is considered a manifestation of sporadic cerebral
small vessel disease and an important pathological substrate for dementia. Asia is notable …

[HTML][HTML] Accuracy of support-vector machines for diagnosis of Alzheimer's disease, using volume of brain obtained by structural MRI at Siriraj hospital

Y Vichianin, A Khummongkol, P Chiewvit… - Frontiers in …, 2021 - frontiersin.org
Background: The determination of brain volumes using visual ratings is associated with an
inherently low accuracy for the diagnosis of Alzheimer's disease (AD). A support-vector …

White matter network damage mediates association between cerebrovascular disease and cognition

S Hilal, S Liu, TY Wong, H Vrooman… - Journal of Cerebral …, 2021 - journals.sagepub.com
To determine whether white matter network disruption mediates the association between
MRI markers of cerebrovascular disease (CeVD) and cognitive impairment. Participants (n …

Clinical management of cerebral small vessel disease: a call for a holistic approach

U Clancy, JP Appleton, C Arteaga, FN Doubal… - Chinese medical …, 2021 - mednexus.org
Cerebral small vessel disease (SVD) is a common global brain disease that causes
cognitive impairment, ischemic or hemorrhagic stroke, problems with mobility, and …

[HTML][HTML] Endothelial dysfunction and hyperhomocysteinemia-linked cerebral small vessel disease: underlying mechanisms and treatment timing

S Li, G Li, X Luo, Y Huang, L Wen, J Li - Frontiers in neurology, 2021 - frontiersin.org
Cerebral small vessel disease (cSVD)—a common cause of stroke and vascular dementia—
is a group of clinical syndromes that affects the brain's small vessels, including arterioles …

[HTML][HTML] Dementia in Southeast Asia: influence of onset-type, education, and cerebrovascular disease

A Vipin, V Satish, SE Saffari, W Koh, L Lim… - Alzheimer's Research & …, 2021 - Springer
Abstract Background Southeast Asia represents 10% of the global population, yet little is
known about regional clinical characteristics of dementia and risk factors for dementia …