Molecular characterization of membrane steroid receptors in hormone-sensitive cancers
Cancer is one of the most common causes of death worldwide, and its development is a
result of the complex interaction of genetic factors, environmental cues, and aging. Hormone …
result of the complex interaction of genetic factors, environmental cues, and aging. Hormone …
Therapeutic potential of TRPM8 antagonists in prostate cancer
M Di Donato, C Ostacolo, P Giovannelli, V Di Sarno… - Scientific reports, 2021 - nature.com
Transient receptor potential melastatin-8 (TRPM8) represents an emerging target in prostate
cancer, although its mechanism of action remains unclear. Here, we have characterized and …
cancer, although its mechanism of action remains unclear. Here, we have characterized and …
Binding of androgen-and estrogen-like flavonoids to their cognate (non) nuclear receptors: a comparison by computational prediction
Flavonoids are plant bioactives that are recognized as hormone-like polyphenols because
of their similarity to the endogenous sex steroids 17β-estradiol and testosterone, and to their …
of their similarity to the endogenous sex steroids 17β-estradiol and testosterone, and to their …
Outcasts and saboteurs: Intervention strategies to reduce the negative effects of social exclusion on team outcomes
The experience of social exclusion in the workplace adversely impacts employees' well-
being, job satisfaction, and productivity, and no one quite knows what to do about it. In this …
being, job satisfaction, and productivity, and no one quite knows what to do about it. In this …
[HTML][HTML] TRPM8 protein expression in hormone naïve local and lymph node metastatic prostate cancer
A Lunardi, M Barbareschi, FG Carbone, L Morelli… - Pathologica, 2021 - ncbi.nlm.nih.gov
Objective Prostate cancer (PCa) is the second most common malignancy in men.
Radiotherapy and surgery successfully control organ-confined tumors, although, locally …
Radiotherapy and surgery successfully control organ-confined tumors, although, locally …
[HTML][HTML] Tune the channel: TRPM8 targeting in prostate cancer
A Alaimo, D De Felice, S Genovesi, M Lorenzoni… - …, 2021 - ncbi.nlm.nih.gov
The therapeutic landscape of cancer treatments is quickly evolving thanks to the advent of
precision oncology. Discovery of novel druggable targets and more reliable biomarkers is a …
precision oncology. Discovery of novel druggable targets and more reliable biomarkers is a …
SSIG: single‐sample information gain model for integrating multi‐omics data to identify cancer subtypes
Z Yuanyuan, W Ziqi, W Shudong… - Chinese Journal of …, 2021 - Wiley Online Library
Different living environments of cancer samples lead to different molecular mechanisms of
cancer development, which in turn leads to different cancer subtypes. How to identify cancer …
cancer development, which in turn leads to different cancer subtypes. How to identify cancer …
Prostate cancer cell lines, gene signatures and uses thereof
RG Pestell - US Patent 10,952,415, 2021 - Google Patents
The present disclosure, in part, is directed to a mammalian prostate cancer cell line
comprising at least one or a set of primary mammalian epithelial cells which have been …
comprising at least one or a set of primary mammalian epithelial cells which have been …
Gene signatures for cancer prognosis
S Stone, A Gutin, J Reid - US Patent 11,174,517, 2021 - Google Patents
US11174517B2 - Gene signatures for cancer prognosis - Google Patents US11174517B2 -
Gene signatures for cancer prognosis - Google Patents Gene signatures for cancer prognosis …
Gene signatures for cancer prognosis - Google Patents Gene signatures for cancer prognosis …
Gene signatures for cancer prognosis
S Stone, A Gutin, S Wagner, JE Reid - US Patent 10,954,568, 2021 - Google Patents
2005/0244872 A1 2005/0272644 A1 2007/0026424 A1 2007/0059720 A9 2007/0099209
A1 2007/0128599 A1 2007/0128636 A1 2007/0253953 A1 2008/0275652 A1 …
A1 2007/0128599 A1 2007/0128636 A1 2007/0253953 A1 2008/0275652 A1 …