Osteoarthritis (OA) is a degenerative joint disease in the elderly. Although OA has been
considered as primarily a disease of the articular cartilage, the participation of subchondral …

With the reignited push for manned spaceflight and the development of companies focused
on commercializing spaceflight, increased human ventures into space are inevitable …

Osteoarthritis (OA) is a whole-joint disease characterized by subchondral bone perfusion
abnormalities and neovascular invasion into the synovium and articular cartilage. In addition …

Osteoarthritis (OA) is currently the most widespread musculoskeletal condition and primarily
affects weight-bearing joints such as the knees and hips. Importantly, knee OA remains a …

Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe, debilitating
condition affecting patients with cancer and patients with osteoporosis who have been …

Osteolytic bone lesions, which develop in many metastatic breast cancer patients, impair
bone integrity and lead to adverse skeletal related events that are difficult to treat and …

Fatigue is a common cause of bone failure. As the main load-bearing tissue, cortical bone
carries a considerable share of load in the whole bone. Under cyclic loading condition …

Bone regeneration is a popular research focus around the world. Recent studies have
suggested that the formation of a vascular network as well as intrinsic osteogenic ability is …

Bisphosphonates (BPs) are a mainstay of osteoporosis treatment; however, concerns about
bone health based on oversuppression of remodeling remain. Long term bone remodeling …

Extracellular adenosine triphosphate (ATP) plays a central role in a wide variety of joint
diseases. ATP is generated intracellularly, and the concentration of the extracellular ATP …