Targeting circular RNAs as a therapeutic approach: current strategies and challenges
Significant progress has been made in circular RNA (circRNA) research in recent years.
Increasing evidence suggests that circRNAs play important roles in many cellular processes …
Increasing evidence suggests that circRNAs play important roles in many cellular processes …
CircRNA in cancer: fundamental mechanism and clinical potential
Abstract Circular RNAs (CircRNAs) are a class of single-stranded noncoding RNAs that are
formed in a circular conformation via non-canonical splicing or back-splicing events …
formed in a circular conformation via non-canonical splicing or back-splicing events …
CircRNAs: role in human diseases and potential use as biomarkers
L Verduci, E Tarcitano, S Strano, Y Yarden… - Cell death & …, 2021 - nature.com
Circular RNAs (circRNAs) are a class of endogenous RNAs characterized by a covalent
loop structure. In comparison to other types of RNAs, the abundance of circRNAs is relatively …
loop structure. In comparison to other types of RNAs, the abundance of circRNAs is relatively …
[HTML][HTML] Review on circular RNAs and new insights into their roles in cancer
X Tang, H Ren, M Guo, J Qian, Y Yang, C Gu - … and structural biotechnology …, 2021 - Elsevier
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …
Circular RNAs and complex diseases: from experimental results to computational models
Circular RNAs (circRNAs) are a class of single-stranded, covalently closed RNA molecules
with a variety of biological functions. Studies have shown that circRNAs are involved in a …
with a variety of biological functions. Studies have shown that circRNAs are involved in a …
Circular RNAs: characteristics, biogenesis, mechanisms and functions in liver cancer
H Shen, B Liu, J Xu, B Zhang, Y Wang, L Shi… - Journal of Hematology & …, 2021 - Springer
Background Hepatocellular carcinoma (HCC) is one of the most common malignancies
globally. Despite aggressive and multimodal treatment regimens, the overall survival of HCC …
globally. Despite aggressive and multimodal treatment regimens, the overall survival of HCC …
Expression profiles, biological functions and clinical significance of circRNAs in bladder cancer
X Yang, T Ye, H Liu, P Lv, C Duan, X Wu, K Jiang, H Lu… - Molecular cancer, 2021 - Springer
Circular RNAs (circRNAs), which are single-stranded closed-loop RNA molecules lacking
terminal 5′ caps and 3′ poly (A) tails, are attracting increasing scientific attention for their …
terminal 5′ caps and 3′ poly (A) tails, are attracting increasing scientific attention for their …
Circular RNAs in kidney disease and cancer
Circular RNAs (circRNAs) are a class of endogenously expressed regulatory RNAs with a
single-stranded circular structure. They are generated by back splicing and their expression …
single-stranded circular structure. They are generated by back splicing and their expression …
[HTML][HTML] Circular RNA circDLC1 inhibits MMP1-mediated liver cancer progression via interaction with HuR
H Liu, T Lan, H Li, L Xu, X Chen, H Liao, X Chen… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: circular RNAs (circRNAs) have been demonstrated to play a crucial role in cancer
progression. KIAA1429, a key component of the m6A methyltransferase complex, has …
progression. KIAA1429, a key component of the m6A methyltransferase complex, has …
[HTML][HTML] circDCUN1D4 suppresses tumor metastasis and glycolysis in lung adenocarcinoma by stabilizing TXNIP expression
Y Liang, H Wang, B Chen, Q Mao, W Xia… - … Therapy-Nucleic Acids, 2021 - cell.com
Aberrant expression of circular RNAs (circRNAs) is involved in cancer progression through
interaction with RNA-binding proteins (RBPs). Herein, we screened circRNA expression of …
interaction with RNA-binding proteins (RBPs). Herein, we screened circRNA expression of …