Dysregulation of the inflammatory response in humans can lead to various inflammatory
diseases, like asthma and rheumatoid arthritis. The innate branch of the immune system …

The p38 mitogen-activated protein kinases (p38 MAPK) is a 38kD polypeptide recognized
as the target for many potential anti-inflammatory agents. Accumulating evidence indicates …

Abstract Ethnopharmacological relevance Physalis Calyx seu Fructus is typically used to
treat inflammatory diseases such as upper respiratory tract infection and acute tonsillitis in …

Abstract Background Polyphyllin VII (PP7), a steroidal saponin from P. polyphylla has been
found to exert strong anticancer activity. Little is known about the anti-angiogenesis and anti …

Bakuchiol (BAK) has been reported to have a diverse pharmacological property as an
antibiotic, anti-cancer, anti-hypolipidemic, anti-inflammatory and anti-convulsant agent. This …

Acne vulgaris (AV) is a chronic skin disease involving inflammation of the pilosebaceous
units. Propionibacterium acnes (P. acnes) hypercolonization is one pathogenic factor for AV …

Ovarian cancer is a gynecological malignancy with high mortality. Adjuvant therapy such as
chemoradiotherapy inevitably leads to side effects and drug resistance. In recent years …

Cancer is the leading cause of mortality in the world. The major therapies for cancer
treatment are chemotherapy, surgery, and radiation therapy. All these therapies expensive …

Steroidal saponins named polyphyllin are the major active components of Paris polyphylla.
Cycloartenol synthase (CAS) is a key enzyme that catalyzes the formation of the sterol …

Cancer is the second leading cause of mortality worldwide. Conventional therapies,
including surgery, radiation, and chemotherapy, have limited success because of secondary …