Disease-induced changes in salivary gland function and the composition of saliva

GB Proctor, AM Shaalan - Journal of dental research, 2021 - journals.sagepub.com
Although the physiological control of salivary secretion has been well studied, the impact of
disease on salivary gland function and how this changes the composition and function of …

Microfluidics for liquid biopsies: recent advances, current challenges, and future directions

Y Belotti, CT Lim - Analytical chemistry, 2021 - ACS Publications
Liquid biopsy has seen tremendous progress over the past decade as it represents a
potential innovative solution to several limitations of current cancer management. By …

Biochemical analysis of oral fluids for disease detection

Z Khurshid, I Warsi, SF Moin, PD Slowey, M Latif… - Advances in clinical …, 2021 - Elsevier
The field of diagnostics using invasive blood testing represents the majority of diagnostic
tests used as part of routine health monitoring. The relatively recent introduction of salivary …

Salivary biomarkers in patients with Sjögren's Syndrome—A systematic review

JY Jung, JW Kim, HA Kim, CH Suh - International Journal of Molecular …, 2021 - mdpi.com
Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by dry mouth and
dry eyes, with lymphocytic infiltration of the exocrine glands. Saliva is becoming a useful tool …

Human body-fluid proteome: quantitative profiling and computational prediction

L Huang, D Shao, Y Wang, X Cui, Y Li… - Briefings in …, 2021 - academic.oup.com
Empowered by the advancement of high-throughput bio technologies, recent research on
body-fluid proteomes has led to the discoveries of numerous novel disease biomarkers and …

The potential impact of salivary IL-1 on the diagnosis of periodontal disease: a pilot study

JY Kim, KR Kim, HN Kim - Healthcare, 2021 - mdpi.com
The aim of this study was to identify inflammatory cytokines as salivary biomarkers for
periodontal disease. The subjects were 33 Korean adults aged 23 to 71 years. Using a …

Differentially expressed gene pathways in the conjunctiva of Sjögren syndrome keratoconjunctivitis sicca

CS de Paiva, CM Trujillo-Vargas, L Schaefer… - Frontiers in …, 2021 - frontiersin.org
Sjögren syndrome (SS) is an autoimmune condition that targets the salivary and lacrimal
glands, with cardinal clinical signs of dry eye (keratoconjunctivitis sicca, KCS) and dry …

A comprehensive database for integrated analysis of omics data in autoimmune diseases

J Martorell-Marugán, R López-Domínguez… - BMC …, 2021 - Springer
Background Autoimmune diseases are heterogeneous pathologies with difficult diagnosis
and few therapeutic options. In the last decade, several omics studies have provided …

The effect of conventional versus electronic cigarette use on treatment outcomes of peri-implant disease

R AlJasser, M Zahid, M AlSarhan, D AlOtaibi… - BMC oral health, 2021 - Springer
Aim To compare changes in clinical periodontal parameters (gingival consistency, colour,
BOP, PI, PD) and changes of salivary inflammatory biomarkers (IL-1 β, IL-6, MMP-8, TNF-α …

New frontiers in precision medicine for Sjogren's syndrome

L Chatzis, PG Vlachoyiannopoulos… - Expert review of …, 2021 - Taylor & Francis
Introduction: Sjögren's syndrome is a unique systemic autoimmune disease, placed in the
center of systemic autoimmunity and at the crossroads of autoimmunity and …