One of the most important regulatory small molecules in plants is indole-3-acetic acid, also
known as auxin. Its dynamic redistribution has an essential role in almost every aspect of …

Rapid, inexpensive, and laboratory-free diagnostic of viral pathogens is highly critical in
controlling viral pandemics. In recent years, nanopore-based sensors have been employed …

The past 4 decades have seen remarkable advances in our understanding of the structural
basis of gene regulation. Technological advances in protein expression, nucleic acid …

Principles of Nucleic Acid Structure, Second Edition, provides the most complete and
concise summary of underlying principles and approaches to studying nucleic acid structure …

Dynamic hydrogen-bond networks provide proteins with structural plasticity required to
translate signals such as ligand binding into a cellular response or to transport ions and …

In natural communities, microbes exchange a variety of metabolites (public goods) with each
other, which drives the evolution of auxotroph and shapes interdependent patterns at …

The obligate intracellular pathogen Chlamydia trachomatis (Ct) is the leading cause of
bacterial sexually transmitted infections and blindness globally. To date, Ct urogenital …

Zta, the Epstein–Barr virus bZIP transcription factor (TF), binds both unmethylated and
methylated double-stranded DNA (dsDNA) in a sequence-specific manner. We studied the …

The tumor suppressor protein p53 is situated in the midst of a complex network that is
activated in response to cellular stress. An unresolved question is how p53 activates its …

The crystal structures of domain-swapped tryptophan repressor (TrpR) variant Val58Ile
before and after soaking with the physiological ligand l-tryptophan (l-Trp) indicate that l-Trp …