[HTML][HTML] Biological characteristics of IL-6 and related intestinal diseases

Y Guo, B Wang, T Wang, L Gao, Z Yang… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
The intestine serves as an important digestive and the largest immune organ in the body.
Interleukin-6 (IL-6), an important mediator of various pathways, participates in the …

Investigating the Potential for Sulforaphane to Attenuate Gastrointestinal Dysfunction in mdx Dystrophic Mice

K Swiderski, SJ Read, AS Chan, JD Chung, J Trieu… - Nutrients, 2021 - mdpi.com
Gastrointestinal (GI) dysfunction is an important, yet understudied condition associated with
Duchenne muscular dystrophy (DMD), with patients reporting bloating, diarrhea, and …

CircORC2 is involved in the pathogenesis of slow transit constipation via modulating the signalling of miR‐19a and neurotensin/motilin

YY Wang, RY Lu, J Shi, S Zhao… - Journal of Cellular and …, 2021 - Wiley Online Library
In this study, we aimed to investigate the role of circORC2 in modulating miR‐19a and its
downstream signalling during the pathogenesis of STC. In this study, three groups of …

Divergent effects of exendin‐4 and interleukin‐6 on rat colonic secretory and contractile activity are associated with changes in regional vagal afferent signaling

R O'Brien, MM Buckley… - Neurogastroenterology & …, 2021 - Wiley Online Library
Background The pro‐inflammatory cytokine, interleukin (IL)‐6 is elevated in individuals with
the functional bowel disorder, irritable bowel syndrome (IBS). IL‐6 can independently modify …