The role of angiogenesis in the growth of organs and tumors is widely recognized. Vascular–
organ interaction is a key mechanism and a concept that enables an understanding of all …

Cancer cells are disordered by nature and thus featured by higher internal redox level than
healthy cells. Redox imbalance could trigger programmed cell death if exceeded a certain …

Background Anatomic interventions for pulmonary vein stenosis (PVS) in infants and
children have been met with limited success. Sirolimus, a mammalian target of rapamycin …

Renal cell carcinoma (RCC) is one of the leading causes of cancer‐related death
worldwide. Tumour metastasis and heterogeneity lead to poor survival outcomes and drug …

Background Temsirolimus is an mTOR antagonist with proven anticancer efficacy.
Preclinical data suggest greater anticancer effect when mTOR inhibitors are combined with …

Renal cell carcinoma represents the most common malignancy of the kidney and the
majority of cases are categorized as clear cell carcinomas. The elucidation of the specific …

Microalgae, one of the most important classes of biomass producers, can produce
exopolysaccharides similar to bacteria. The exopolysaccharide from Chlorella (CEPS) …

Results: Twenty-six patients were treated in this study in 4 cohorts and dose levels. Fourteen
males and 12 females were enrolled with a median age of 50 years (range of 27 to 72 y) and …

Simple Summary Interstitial lung disease is a group of diseases characterized by chronic
lung inflammation that can be related to oncological treatments, such as traditional …

With the development of molecular targeted therapies, a wide array of dermatologic toxicities
is appearing. Their prevention, recognition, and management by dermatologists is critical to …