SARS-CoV-2, COVID-19 and the aging immune system
JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …
particular risk for severe disease and death in older adults and in adults with age-related …
[HTML][HTML] The first 12 months of COVID-19: a timeline of immunological insights
Since the initial reports of a cluster of pneumonia cases of unidentified origin in Wuhan,
China, in December 2019, the novel coronavirus that causes this disease—severe acute …
China, in December 2019, the novel coronavirus that causes this disease—severe acute …
Single-cell multi-omics analysis of the immune response in COVID-19
Abstract Analysis of human blood immune cells provides insights into the coordinated
response to viral infections such as severe acute respiratory syndrome coronavirus 2, which …
response to viral infections such as severe acute respiratory syndrome coronavirus 2, which …
[HTML][HTML] SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans
Long-lived bone marrow plasma cells (BMPCs) are a persistent and essential source of
protective antibodies 1, 2, 3, 4, 5, 6, 7. Individuals who have recovered from COVID-19 have …
protective antibodies 1, 2, 3, 4, 5, 6, 7. Individuals who have recovered from COVID-19 have …
[HTML][HTML] Evolution of antibody immunity to SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected 78 million
individuals and is responsible for over 1.7 million deaths to date. Infection is associated with …
individuals and is responsible for over 1.7 million deaths to date. Infection is associated with …
New-onset IgG autoantibodies in hospitalized patients with COVID-19
SE Chang, A Feng, W Meng, SA Apostolidis… - Nature …, 2021 - nature.com
COVID-19 is associated with a wide range of clinical manifestations, including autoimmune
features and autoantibody production. Here we develop three protein arrays to measure IgG …
features and autoantibody production. Here we develop three protein arrays to measure IgG …
BNT162b2 vaccination induces durable SARS-CoV-2–specific T cells with a stem cell memory phenotype
G Guerrera, M Picozza, S D'Orso, R Placido… - Science …, 2021 - science.org
Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
effective in preventing hospitalization from severe COVID-19. However, multiple reports of …
effective in preventing hospitalization from severe COVID-19. However, multiple reports of …
[HTML][HTML] Functional SARS-CoV-2-specific immune memory persists after mild COVID-19
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is causing a
global pandemic, and cases continue to rise. Most infected individuals experience mildly …
global pandemic, and cases continue to rise. Most infected individuals experience mildly …
SARS-CoV-2 infection generates tissue-localized immunological memory in humans
Adaptive immune responses to SARS-CoV-2 infection have been extensively characterized
in blood; however, most functions of protective immunity must be accomplished in tissues …
in blood; however, most functions of protective immunity must be accomplished in tissues …
Delayed production of neutralizing antibodies correlates with fatal COVID-19
Recent studies have provided insights into innate and adaptive immune dynamics in
coronavirus disease 2019 (COVID-19). However, the exact features of antibody responses …
coronavirus disease 2019 (COVID-19). However, the exact features of antibody responses …