[HTML][HTML] Role of lysosomes in physiological activities, diseases, and therapy

Z Zhang, P Yue, T Lu, Y Wang, Y Wei, X Wei - Journal of hematology & …, 2021 - Springer
Long known as digestive organelles, lysosomes have now emerged as multifaceted centers
responsible for degradation, nutrient sensing, and immunity. Growing evidence also …

The Tabula Sapiens: a single cell transcriptomic atlas of multiple organs from individual human donors

Tabula Sapiens Consortium, SR Quake - Biorxiv, 2021 - biorxiv.org
In recent years there has been tremendous progress towards deep molecular
characterization of cell types using single cell transcriptome sequencing. Here we report a …

[HTML][HTML] The role of inflammation in breast and prostate cancer metastasis to bone

A Göbel, S Dell'Endice, N Jaschke, S Pählig… - International Journal of …, 2021 - mdpi.com
Tumor metastasis to bone is a common event in multiple forms of malignancy. Inflammation
holds essential functions in homeostasis as a defense mechanism against infections and is …

[HTML][HTML] Cross talk between macrophages and cancer cells in the bone metastatic environment

L Batoon, LK McCauley - Frontiers in Endocrinology, 2021 - frontiersin.org
The skeleton is a common site for cancer metastases with the bone microenvironment
providing the appropriate conditions for cancer cell colonization. Once in bone, cancer cells …

Effect of Omeprazole on Osteoblasts and Osteoclasts in vivo and in the in vitro Model Using Fish Scales

MI Zanaty, A Abdel-Moneim, Y Kitani, T Sekiguchi… - Biochemistry …, 2021 - Springer
Omeprazole suppresses excessive secretion of gastric acid via irreversible inhibition of
H+/K+-ATPase in the gastric parietal cells. Recent meta-analysis of data revealed an …

Single-cell RNA Sequencing Reveals Immunosuppressive Myeloid Cell Diversity and Restricted Cytotoxic Effector Cell Trafficking and Activation During Malignant …

S Rajendran, C Peterson, A Canella, Y Hu, A Gross… - bioRxiv, 2021 - biorxiv.org
Low grade gliomas (LGG) account for about two-thirds of all glioma diagnoses in
adolescents and young adults (AYA) and malignant progression of these patients leads to …

ВЛИЯНИЕ ОМЕПРАЗОЛА НА ОСТЕОБЛАСТЫ И ОСТЕОКЛАСТЫ in vivo И В МОДЕЛИ in vitro С ИСПОЛЬЗОВАНИЕМ ЧЕШУИ РЫБЫ

MI Zanaty, A Abdel-Moneim, Y Kitani, T Sekiguchi… - Биохимия, 2021 - elibrary.ru
Омепразол подавляет чрезмерную секрецию кислоты желудочного сока за счет
необратимого ингибирования H+/K+-ATPазы в париетальных клетках желудка …