Effects of (−)-epigallocatechin-3-gallate on the functional and structural properties of soybean protein isolate

Y You, L Yang, H Chen, L Xiong… - Journal of Agricultural and …, 2021 - ACS Publications
In the present study, soy protein isolate (SPI) was noncovalently modified by (−)-
epigallocatechin-3-gallate (EGCG), and its foaming, emulsifying, and antioxidant properties …

The effect of sorbitol on the structure and activity of carboxypeptidase A: Insights from a spectroscopic and computational approach

M Mohammadi, B Shareghi, S Farhadian… - Journal of Molecular …, 2021 - Elsevier
In this research, the effect of sorbitol on the structure, thermal stability and activity of native
carboxypeptidase A from bovine pancreas was investigated using ultraviolet–visible (UV …

Synthesis of sorafenib analogues incorporating a 1, 2, 3-triazole ring and cytotoxicity towards hepatocellular carcinoma cell lines

S Palakhachane, Y Ketkaew, N Chuaypen, J Sirirak… - Bioorganic …, 2021 - Elsevier
Abstract A series of 1, 2, 3-triazole-containing Sorafenib analogues, in which the aryl urea
moiety of Sorafenib (1) was replaced with a 1, 2, 3-triazole ring linking a substituted phenoxy …

Elucidating the interaction of enantiomeric Cu (II) complexes with DNA, RNA and HSA: A comparative study

S Parveen, S Jafri, HY Khan, S Tabassum, F Arjmand - Polyhedron, 2021 - Elsevier
To find out the potential of enantiomeric copper complexes (1 S and 1 R) as therapeutics,
interactions studies with three different biomacromolecules (ct-DNA, tRNA and HSA) were …

Sulfated polysaccharide ascophyllan prevents amyloid fibril formation of human insulin and inhibits amyloid-induced hemolysis and cytotoxicity in PC12 cells

Y Liang, M Ueno, S Zha, T Okimura… - Bioscience …, 2021 - academic.oup.com
We found that ascophyllan significantly inhibited the fibrillation of human insulin and was the
most effective among the sulfated polysaccharides tested. Gel-filtration analysis suggested …

A binuclear chloride bridged Cu (II) and a mononuclear Ni (II) complex: Synthesis, crystal structure, photo catalytic and biological studies

K Jana, R Maity, H Puschmann, A Mitra, R Ghosh… - Inorganica Chimica …, 2021 - Elsevier
In the present paper, one new binuclear chloride bridged Cu (II) complex [Cl 2 Cu-(μ-Cl)-Cu
(L) Cl 2](1) and one mononuclear Ni (II) complex [Ni (L′) 2](ClO 4) 2 (2) where L= N 1 …

In silico prediction, molecular docking and binding studies of acetaminophen and dexamethasone to Enterococcus faecalis diaminopimelate epimerase

H Singh, S Das, J Yadav, VK Srivastava… - Journal of Molecular …, 2021 - Wiley Online Library
Enterococcus faecalis (E. faecalis) is a Gram‐positive coccoid, non‐sporulating, facultative
anaerobic, multidrug resistance bacterium responsible for almost 65% to 80% of all …

Nanoclay based study on protein stability and aggregation and its implication in human health

R Parveen, Z Tarannum, S Ali, S Fatima - International Journal of Biological …, 2021 - Elsevier
Protein aggregation is the major cause of several acute amyloid diseases such as
Parkinson's, Huntington's, Alzheimer's, Lysozyme Systemic amyloidosis, Diabetes-II etc …

Biophysical insight into the interaction of levocabastine with human serum albumin: spectroscopy and molecular docking approach

FM Almutairi, MR Ajmal, MK Siddiqi… - Journal of …, 2021 - Taylor & Francis
Interaction of levocabastine with human serum albumin (HSA) is investigated by applying
fluorescence spectroscopy, circular dichroism spectroscopy and molecular docking …

Inhibition of Amyloid Fibrillation of HEWL by 4-Methylcoumarin and 4-Methylthiocoumarin Derivatives

S Kumar, M Kumar, YK Tyagi… - Current pharmaceutical …, 2021 - ingentaconnect.com
Background: Several human diseases like Parkinson's, Alzheimer's disease, and systemic
amyloidosis are associated with the misfolding and aggregation of protein molecules …