[HTML][HTML] StructureMan: A structure manipulation tool to study large scale biomolecular interactions
Studying biomolecular interactions is a crucial but challenging task. Due to their large
scales, many biomolecular interactions are difficult to be simulated via all atom models. An …
scales, many biomolecular interactions are difficult to be simulated via all atom models. An …
Methods for molecular modelling of protein complexes
Biological processes are often mediated by complexes formed between proteins and
various biomolecules. The 3D structures of such protein–biomolecule complexes provide …
various biomolecules. The 3D structures of such protein–biomolecule complexes provide …
[HTML][HTML] RBPSpot: Learning on appropriate contextual information for RBP binding sites discovery
Identifying the factors determining the RBP-RNA interactions remains a big challenge. It
involves sparse binding motifs and a suitable sequence context for binding. The present …
involves sparse binding motifs and a suitable sequence context for binding. The present …
[HTML][HTML] RPocket: an intuitive database of RNA pocket topology information with RNA-ligand data resources
Background RNA regulates a variety of biological functions by interacting with other
molecules. The ligand often binds in the RNA pocket to trigger structural changes or …
molecules. The ligand often binds in the RNA pocket to trigger structural changes or …
HISNAPI: a bioinformatic tool for dynamic hot spot analysis in nucleic acid–protein interface with a case study
LC Mei, YL Wang, FX Wu, F Wang… - Briefings in …, 2021 - academic.oup.com
Protein–nucleic acid interactions play essential roles in many biological processes, such as
transcription, replication and translation. In protein–nucleic acid interfaces, hotspot residues …
transcription, replication and translation. In protein–nucleic acid interfaces, hotspot residues …
[HTML][HTML] Staring at the Naked Goddess: Unraveling the Structure and Reactivity of Artemis Endonuclease Interacting with a DNA Double Strand
Artemis is an endonuclease responsible for breaking hairpin DNA strands during immune
system adaptation and maturation as well as the processing of potentially toxic DNA lesions …
system adaptation and maturation as well as the processing of potentially toxic DNA lesions …
SARS-CoV-2 infects lung epithelial cells and induces senescence and an inflammatory response in patients with severe COVID-19
K Evangelou, D Veroutis, PG Foukas, K Paschalaki… - bioRxiv, 2021 - biorxiv.org
Rationale SARS-CoV-2 infection of the respiratory system can progress to a life threatening
multi-systemic disease, mediated via an excess of cytokines (“cytokine storm”), but the …
multi-systemic disease, mediated via an excess of cytokines (“cytokine storm”), but the …