Guided versus standard antiplatelet therapy in patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis

M Galli, S Benenati, D Capodanno, F Franchi, F Rollini… - The Lancet, 2021 - thelancet.com
Background Whether guided selection of antiplatelet therapy in patients undergoing
percutaneous coronary intervention (PCI) is effective in improving outcomes compared with …

Evolution of antithrombotic therapy in patients undergoing percutaneous coronary intervention: a 40-year journey

D Cao, R Chandiramani, M Chiarito… - European Heart …, 2021 - academic.oup.com
Since its introduction in 1977, percutaneous coronary intervention has become one of the
most commonly performed therapeutic procedures worldwide. Such widespread diffusion …

2020 ACC expert consensus decision pathway for anticoagulant and antiplatelet therapy in patients with atrial fibrillation or venous thromboembolism undergoing …

DJ Kumbhani, CP Cannon, CJ Beavers… - Journal of the American …, 2021 - jacc.org
The American College of Cardiology (ACC) has a long history of developing documents (eg,
decision pathways, health policy statements, appropriate use criteria) to provide members …

Genetic testing in patients undergoing percutaneous coronary intervention: rationale, evidence and practical recommendations

M Galli, F Franchi, F Rollini, LH Cavallari… - Expert review of …, 2021 - Taylor & Francis
Introduction Clopidogrel is the most frequently utilized P2Y12 inhibitor and is characterized
by broad interindividual response variability resulting in impaired platelet inhibition and …

[HTML][HTML] MicroRNA as potential biomarkers of platelet function on antiplatelet therapy: a review

P Czajka, A Fitas, D Jakubik, C Eyileten… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs) are small, non-coding RNAs, able to regulate cellular functions by
specific gene modifications. Platelets are the major source for circulating miRNAs, with …

Stent thrombosis risk over time on the basis of clinical presentation and platelet reactivity: analysis from ADAPT-DES

KH Chau, AJ Kirtane, RM Easterwood… - Cardiovascular …, 2021 - jacc.org
Objectives The aim of this study was to determine the risk period for increased stent
thrombosis (ST) after percutaneous coronary intervention (PCI) in patients with acute …

Guided P2Y12 inhibitor therapy after percutaneous coronary intervention

D Sibbing, A Kastrati - The Lancet, 2021 - thelancet.com
2 McMahan K, Yu J, Mercado NB, et al. Correlates of protection against SARS-CoV-2 in
rhesus macaques. Nature 2021; 590: 630–34. 3 Yu J, Tostanoski LH, Peter L, et al. DNA …

[HTML][HTML] Clopidogrel monotherapy in patients with and without on-treatment high platelet reactivity: a SMART-CHOICE substudy: Impact of HPR on clopidogrel …

S Lee, S Lee, W Chun, Y Song, SH Choi… - …, 2021 - ncbi.nlm.nih.gov
Background Although P2Y 12 inhibitor monotherapy has emerged as a promising
alternative for dual antiplatelet therapy (DAPT), there remains concern regarding the safety …

[HTML][HTML] CHADS2 and CHA2DS2-VASc scores as predictors of platelet reactivity in acute coronary syndrome

E Asher, A Abu-Much, NL Bragazzi, A Younis… - Journal of …, 2021 - Elsevier
Background Platelet function testing (PFT) in patients treated with P2Y 12 inhibitors has
been widely evaluated for the prediction of stent thrombosis, myocardial infarction, and …

Effects of clopidogrel, prasugrel and ticagrelor on prevention of stent thrombosis in patients underwent percutaneous coronary intervention: A network meta‐analysis

W Chen, C Zhang, J Zhao, X Xu, H Dang… - Clinical …, 2021 - Wiley Online Library
Background Clopidogrel, prasugrel and ticagrelor, acting on platelet P2Y12 receptor, are
commonly used for prevention of stent thrombosis (ST) among patients who underwent …