Acute myeloid leukemia is characterized by arrested differentiation, and agents that
overcome this block are therapeutically useful, as shown by the efficacy of all-trans retinoic …

Research has resulted in regulatory approval of nine agents for acute myeloid leukaemia
indications by the US Food and Drug Administration since 2017: the Bcl-2 inhibitor …

To design a simple and reproducible classifier predicting the overall survival (OS) of patients
with acute myeloid leukemia (AML)≥ 60 years of age treated with 7+ 3, we sequenced 37 …

The retinoic acid receptors (RARA, RARB, and RARG) are ligand-regulated nuclear
receptors that act as transcriptional switches. These master genes drew significant interest in …

Retinoic acid (RA) was proposed to increase survival of chemotherapy-treated patients with
nucleophosmin-1 (NPM-1c)-mutated acute myeloid leukemia. We reported that, ex vivo, RA …

Acute myeloid leukemia (AML) is predominantly a disease of older age, with a median age
of 68 years at diagnosis. 1 Older and unfit adults with AML (herein defined as age $60 …

Even though allogeneic stem cell transplantation is the most intensive treatment for acute
myeloid leukemia (AML), chemo-resistant leukemia relapse is still one of the most common …

Настоящий обзор посвящен анализу теоретической базы и проводимой в клинике НИИ
детской онкологии, гематологии и трансплантологии им. РМ Горбачевой терапии …

The retinoids all-trans retinoic acid (ATRA) and bexarotene are active in acute myeloid
leukemia (AML), but responses beyond acute promyelocytic leukemia (APL) have been …

To design a simple and reproducible classifier predicting the overall survival (OS) of AML
patients≥ 60 years old treated with 7+ 3, we sequenced 37 genes in 471 patients from the …