As a key regulator of cellular calcium homeostasis, the Sarcoendoplasmic Reticulum
Calcium ATPase (SERCA) pump acts to transport calcium ions from the cytosol back to the …

Duchenne muscular dystrophy (DMD) is an X-linked muscle-wasting disease caused by the
loss of dystrophin. DMD is associated with muscle degeneration, necrosis, inflammation …

Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder characterized by
progressive muscular weakness because of the loss of dystrophin. Extracellular Ca2+ flows …

Objective NAD+ is a co-factor and substrate for enzymes maintaining energy homeostasis.
Nicotinamide phosphoribosyltransferase (NAMPT) controls NAD+ synthesis, and in skeletal …

Of the many crucial functions of the ER, homeostasis of physiological calcium increase is
critical for signaling. Plasma membrane (PM) injury causes a pathological calcium influx …

Imbalances in redox homeostasis can result in oxidative stress, which is implicated in
various pathological conditions including the fatal neuromuscular disease Duchenne …

Store-operated Ca2+ entry (SOCE) is a ubiquitous mechanism regulating extracellular Ca2+
entry to control a multitude of Ca2+-dependent signaling pathways and cellular processes …

Influenza A virus is an important human pathogen, causing significant morbidity and
mortality. Numerous host factors and cellular responses are dysregulated during influenza A …

Skeletal muscle mitochondria are placed in close proximity of the sarcoplasmic reticulum
(SR), the main intracellular Ca 2+ store. During muscle activity, excitation of sarcolemma …

Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, is an X‐
linked disease affecting male and rarely adult heterozygous females, resulting in death by …