Periods of synchronized myelin changes shape brain function and plasticity
Myelin, a lipid membrane that wraps axons, enabling fast neurotransmission and metabolic
support to axons, is conventionally thought of as a static structure that is set early in …
support to axons, is conventionally thought of as a static structure that is set early in …
Ensheathment and myelination of axons: evolution of glial functions
Myelination of axons provides the structural basis for rapid saltatory impulse propagation
along vertebrate fiber tracts, a well-established neurophysiological concept. However …
along vertebrate fiber tracts, a well-established neurophysiological concept. However …
[HTML][HTML] Evolution of DNA methylation in the human brain
DNA methylation is a critical regulatory mechanism implicated in development, learning,
memory, and disease in the human brain. Here we have elucidated DNA methylation …
memory, and disease in the human brain. Here we have elucidated DNA methylation …
[PDF][PDF] iPSC-derived myelinoids to study myelin biology of humans
OG James, BT Selvaraj, D Magnani, K Burr… - Developmental Cell, 2021 - cell.com
Myelination is essential for central nervous system (CNS) formation, health, and function.
Emerging evidence of oligodendrocyte heterogeneity in health and disease and divergent …
Emerging evidence of oligodendrocyte heterogeneity in health and disease and divergent …
[HTML][HTML] Microglial ASD-related genes are involved in oligodendrocyte differentiation
Y Takanezawa, S Tanabe, D Kato, R Ozeki… - Scientific reports, 2021 - nature.com
Autism spectrum disorders (ASD) are associated with mutations of chromodomain-helicase
DNA-binding protein 8 (Chd8) and tuberous sclerosis complex 2 (Tsc2). Although these …
DNA-binding protein 8 (Chd8) and tuberous sclerosis complex 2 (Tsc2). Although these …