[HTML][HTML] Metabolomics and complementary techniques to investigate the plant phytochemical cosmos

H Tsugawa, A Rai, K Saito, R Nakabayashi - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to 2021 Plants and their associated microbial communities are known to
produce millions of metabolites, a majority of which are still not characterized and are …

[HTML][HTML] Metabolomics: A scoping review of its role as a tool for disease biomarker discovery in selected non-communicable diseases

AV Aderemi, AO Ayeleso, OO Oyedapo, E Mukwevho - Metabolites, 2021 - mdpi.com
Metabolomics is a branch of 'omics' sciences that utilises a couple of analytical tools for the
identification of small molecules (metabolites) in a given sample. The overarching goal of …

Reviewing the metabolome coverage provided by LC-MS: Focus on sample preparation and chromatography-A tutorial

M Roca, MI Alcoriza, JC Garcia-Cañaveras… - Analytica Chimica Acta, 2021 - Elsevier
Metabolomics has become an invaluable tool for both studying metabolism and biomarker
discovery. The great technical advances in analytical chemistry and bioinformatics have …

[HTML][HTML] Defining blood plasma and serum metabolome by GC-MS

O Kiseleva, I Kurbatov, E Ilgisonis, E Poverennaya - Metabolites, 2021 - mdpi.com
Metabolomics uses advanced analytical chemistry methods to analyze metabolites in
biological samples. The most intensively studied samples are blood and its liquid …

Toxico-metabolomics study of a deep eutectic solvent comprising choline chloride and urea suggests in vivo toxicity involving oxidative stress and ammonia stress

D Jung, JB Jung, S Kang, K Li, I Hwang, JH Jeong… - Green …, 2021 - pubs.rsc.org
Deep eutectic solvents (DESs) comprising safe constituents are generally considered green
and nontoxic without careful assessment. Here, eight different DESs were prepared from …

Investigation and identification of the multiple components of Rheum officinale Baill. using ultra‐high‐performance liquid chromatography coupled with quadrupole …

M Yao, J Li, M He, H Ouyang, L Ruan… - Journal of …, 2021 - Wiley Online Library
Rheum officinale Baill. is a traditional Chinese medicine that has long been used for
eliminating body heat, cooling and detoxifying blood, removing blood stasis and promoting …

Capillary ultrahigh-pressure liquid chromatography-mass spectrometry for fast and high resolution metabolomics separations

MJ Sorensen, RT Kennedy - Journal of Chromatography A, 2021 - Elsevier
LC-MS is an important tool for metabolomics due its high sensitivity and broad metabolite
coverage. The goal of improving resolution and decreasing analysis time in HPLC has led to …

State-of-the-art in LC–MS Approaches for Probing the Polar Metabolome

A Lioupi, M Marinaki, C Virgiliou, H Gika, I Wilson… - 2021 - books.rsc.org
Metabolomics is a rapidly growing research area that focuses on the systematic study of
small molecule metabolites found in various types of biological samples, such as tissues …

Droplet-based extraction mass spectrometry

X Zhang, N Na, J Ouyang - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Analytical methods based on microdroplet technology have made great progress in life
science research. As a new method of sample separation and enrichment, single-drop …

Ultrahigh Pressure Capillary Liquid Chromatography-Mass Spectrometry for Metabolomics and Lipidomics

M Sorensen - 2021 - deepblue.lib.umich.edu
Metabolites and lipids are important compounds involved in various cellular processes. The
comprehensive analysis of all metabolite and lipid species, termed metabolomics and …