Bioinert, stealth or interactive: how surface chemistry of nanocarriers determines their fate in vivo
Nanocarriers (NCs) have emerged as powerful tools to improve drug solubility, to promote
drug transport across membranes, to protect their payload from premature degradation, and …
drug transport across membranes, to protect their payload from premature degradation, and …
Targeting glioblastoma: Advances in drug delivery and novel therapeutic approaches
E Yeini, P Ofek, N Albeck… - Advanced …, 2021 - Wiley Online Library
Glioblastoma (GB) is the most lethal type of primary tumor in the central nervous system.
Current treatments include surgical resection followed by chemotherapy and radiotherapy …
Current treatments include surgical resection followed by chemotherapy and radiotherapy …
Anti‐inflammatory nanotherapeutics by targeting matrix metalloproteinases for immunotherapy of spinal cord injury
Neuroinflammation is critically involved in the repair of spinal cord injury (SCI), and
macrophages associated with inflammation propel the degeneration or recovery in the …
macrophages associated with inflammation propel the degeneration or recovery in the …
Delivery of various cargos into cancer cells and tissues via cell-penetrating peptides: a review of the last decade
A Shoari, R Tooyserkani, M Tahmasebi, DWPM Löwik - Pharmaceutics, 2021 - mdpi.com
Abstracts Cell-penetrating peptides (CPPs), also known as protein transduction domains,
are a class of diverse amino acid sequences with the ability to cross cellular membranes …
are a class of diverse amino acid sequences with the ability to cross cellular membranes …
Brain delivery of Plk1 inhibitor via chimaeric polypeptide polymersomes for safe and superb treatment of orthotopic glioblastoma
Q Fan, Y Liu, G Cui, Z Zhong, C Deng - Journal of Controlled Release, 2021 - Elsevier
The chemotherapy toward glioblastoma (GBM) is severely challenged by blood-brain barrier
and dose-limiting toxicity. Herein, we adopt brain delivery of Plk1 inhibitor volasertib (Vol) …
and dose-limiting toxicity. Herein, we adopt brain delivery of Plk1 inhibitor volasertib (Vol) …
Identification of efficient prokaryotic cell-penetrating peptides with applications in bacterial biotechnology
In bacterial biotechnology, instead of producing functional proteins from plasmids, it is often
necessary to deliver functional proteins directly into live cells for genetic manipulation or …
necessary to deliver functional proteins directly into live cells for genetic manipulation or …
Nanomedicine-based strategies to target and modulate the tumor microenvironment
The interest in nanomedicine for cancer theranostics has grown significantly over the past
few decades. However, these nanomedicines need to overcome several physiological …
few decades. However, these nanomedicines need to overcome several physiological …
[HTML][HTML] Molecular targets and nanoparticulate systems designed for the improved therapeutic intervention in glioblastoma multiforme
Glioblastoma multiforme (GBM) is the most aggressive and fatal CNS related tumors, which
is responsible for about 4% of cancer-related deaths. Current GBM therapy includes surgery …
is responsible for about 4% of cancer-related deaths. Current GBM therapy includes surgery …
Glioblastoma: State of the Art of Treatments and Applications of Polymeric and Lipidic Nanomedicines
V Sgarbi, JT Duskey, I Ottonelli, F Da Ros… - Nanotherapy for Brain …, 2021 - Springer
Glioblastoma multiforme (GBM) is one of the most devastating tumors affecting more than 5
in 100,000 people. Unfortunately, its diagnosis is often discovered in late stages and is …
in 100,000 people. Unfortunately, its diagnosis is often discovered in late stages and is …
Technological challenges of theranostics in oncology
The significance of personalized medicine has been expanding rapidly, mainly due to more
urgent requirement to minimize expensive and irrelevant treatment of cancer. The root of …
urgent requirement to minimize expensive and irrelevant treatment of cancer. The root of …