The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Human gut microbiota harbors numerous microbial species with molecular enzymatic
potential that impact on the eubiosis/dysbiosis and health/disease balances. Microbiota …

Given its uniformly high expression on plasma cells, CD38 has been considered as a
therapeutic target in patients with systemic lupus erythematosus (SLE). Herein, we …

Background: Multiple sclerosis (MS) is characterized by central nervous system (CNS)
infiltration of T and B cells, excess inflammatory cytokine and chemokine production and …

Neonatal and infant immune responses are characterized by a limited capability to generate
protective Ab titers and memory B cells as seen in adults. Multiple studies support an …

The anti-inflammatory role of regulatory B cells (Breg cells) has been associated with IL-35
based on studies of experimental autoimmune uveitis and encephalitis. The role of Breg …

Sarcoidosis and tuberculosis have many clinical and laboratory similarities, which allowed
researchers to assume the presence of common pathogenetic mechanisms in the …

A hallmark of systemic lupus erythematosus (SLE) is aberrant B-cell differentiation and
function, and the pathogenic roles of B cells are multifaceted. In addition to producing …

Background Type 1 diabetes (T1D) is an autoimmune disease with a complex aetiology. B
cells play an important role in the pathogenesis of T1D. Regulatory B cells (Bregs) are a …

Anorexia nervosa (AN) is a severe eating disorder and often associated with altered
humoral immune responses. However, distinct B cell maturation stages in peripheral blood …