Steps in metastasis: an updated review

J Majidpoor, K Mortezaee - Medical Oncology, 2021 - Springer
Metastasis is the most complex and deadly event. Tumor-stromal interface is a place where
invasion of tumor cells in the form of single-cell or collective migration occurs, with the latter …

[HTML][HTML] Biomedical applications and bioavailability of curcumin—An updated overview

SI Sohn, A Priya, B Balasubramaniam… - Pharmaceutics, 2021 - mdpi.com
Curcumin, a yellow-colored molecule derived from the rhizome of Curcuma longa, has been
identified as the bioactive compound responsible for numerous pharmacological activities of …

Immunomodulatory effects of nanocurcumin on Th17 cell responses in mild and severe COVID19 patients

S Tahmasebi, MA ElEsawi… - Journal of cellular …, 2021 - Wiley Online Library
In novel coronavirus disease 2019 (COVID19), the increased frequency and overactivation
of T helper (Th) 17 cells and subsequent production of large amounts of proinflammatory …

Optimization and modeling of microwave-assisted extraction of curcumin and antioxidant compounds from turmeric by using natural deep eutectic solvents

K Doldolova, M Bener, M Lalikoğlu, YS Aşçı, R Arat… - Food Chemistry, 2021 - Elsevier
Natural deep eutectic solvents (NADES) have recently come to the fore as new green
solvents for foods, cosmetics and pharmaceuticals due to their unique solvation power and …

[HTML][HTML] Receptor tyrosine kinases and their signaling pathways as therapeutic targets of curcumin in cancer

S Sudhesh Dev, SA Zainal Abidin… - Frontiers in …, 2021 - frontiersin.org
Receptor tyrosine kinases (RTKs) are transmembrane cell-surface proteins that act as signal
transducers. They regulate essential cellular processes like proliferation, apoptosis …

A tripleblind, placebocontrolled, randomized clinical trial to evaluate the effect of curcumincontaining nanomicelles on cellular immune responses subtypes and …

M Hassaniazad, E Eftekhar… - Phytotherapy …, 2021 - Wiley Online Library
In COVID19 patients, cytokine storm due to excessive immune responses can cause
severe complications. In this study, we investigated the effect of curcumin nanomicelles on …

[HTML][HTML] Targeted delivery of drugs and genes using polymer nanocarriers for cancer therapy

W Xia, Z Tao, B Zhu, W Zhang, C Liu, S Chen… - International journal of …, 2021 - mdpi.com
Cancer is one of the primary causes of worldwide human deaths. Most cancer patients
receive chemotherapy and radiotherapy, but these treatments are usually only partially …

[HTML][HTML] Curcumin and its modified formulations on inflammatory bowel disease (IBD): The story so far and future outlook

A Karthikeyan, KN Young, M Moniruzzaman… - Pharmaceutics, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder
of the small intestine and colon. IBD includes ulcerative colitis (UC) and Crohn's disease …

NanoDerived Therapeutic Formulations with Curcumin in InflammationRelated Diseases

C Quispe, N Cruz-Martins, ML Manca… - Oxidative Medicine …, 2021 - Wiley Online Library
Due to its vast therapeutic potential, the plantderived polyphenol curcumin is utilized in an
evergrowing number of healthrelated applications. Here, we report the extraction …

[HTML][HTML] 3D printed alginate-cellulose nanofibers based patches for local curcumin administration

R Olmos-Juste, B Alonso-Lerma, R Pérez-Jiménez… - Carbohydrate …, 2021 - Elsevier
Alginate and nanocellulose are potential biomaterials to be employed as bioinks for three-
dimensional (3D) printing. Alginate-cellulose nanofibers (A-CNF) formulations with CNF …