Imaging intact human organs with local resolution of cellular structures using hierarchical phase-contrast tomography

CL Walsh, P Tafforeau, WL Wagner, DJ Jafree… - Nature …, 2021 - nature.com
Imaging intact human organs from the organ to the cellular scale in three dimensions is a
goal of biomedical imaging. To meet this challenge, we developed hierarchical phase …

X-ray phase-contrast imaging: a broad overview of some fundamentals

DM Paganin, D Pelliccia - Advances in Imaging and Electron Physics, 2021 - Elsevier
We outline some basics of imaging using both fully-coherent and partially-coherent X-ray
beams, with an emphasis on phase-contrast imaging. We open with some of the basic …

High-resolution and sensitivity bi-directional x-ray phase contrast imaging using 2D Talbot array illuminators

A Gustschin, M Riedel, K Taphorn, C Petrich… - Optica, 2021 - opg.optica.org
Two-dimensional (2D) Talbot array illuminators (TAIs) were designed, fabricated, and
evaluated for high-resolution high-contrast x-ray phase imaging of soft tissue at 10–20 keV …

Propagation-based phase-contrast CT of the breast demonstrates higher quality than conventional absorption-based CT even at lower radiation dose

ST Taba, BD Arhatari, YI Nesterets, Z Gadomkar… - Academic …, 2021 - Elsevier
Rationale and Objectives Propagation-based phase-contrast CT (PB-CT) is an advanced X-
ray imaging technology that exploits both refraction and absorption of the transmitted X-ray …

Improved resolution in x-ray tomography by super-resolution

T Dreier, N Peruzzi, U Lundström, M Bech - Applied Optics, 2021 - opg.optica.org
In this paper, super-resolution imaging is described and evaluated for x-ray tomography and
is compared with standard tomography and upscaling during reconstruction. Blurring is …

Prototype system of noninterferometric phase-contrast computed tomography utilizing medical imaging components

Z Wu, WB Wei, K Gao, G Liu, GF Liu, HX Sun… - Journal of Applied …, 2021 - pubs.aip.org
Grating-based x-ray phase-contrast imaging has been demonstrated to provide more
information and higher-contrast images for low-Z soft tissues, compared with conventional …

X-ray phase-contrast computed tomography for soft tissue imaging at the imaging and medical beamline (IMBL) of the Australian synchrotron

BD Arhatari, AW Stevenson, B Abbey, YI Nesterets… - Applied Sciences, 2021 - mdpi.com
The Imaging and Medical Beamline (IMBL) is a superconducting multipole wiggler-based
beamline at the 3 GeV Australian Synchrotron operated by the Australian Nuclear Science …

X-ray Dark-Field Imaging (XDFI)—A Promising Tool for 3D Virtual Histopathology

D Shimao, N Sunaguchi, T Yuasa, M Ando… - Molecular Imaging and …, 2021 - Springer
X-ray dark-field imaging (XDFI) utilizing a thin silicon crystal under Laue case enables
visualizing three-dimensional (3D) morphological alterations of human tissue. XDFI uses …

High-resolution quantitative phase-contrast x-ray imaging for biomedical samples at PETRA III

M Riedel, A Gustschin, L Ushakov… - Developments in X …, 2021 - spiedigitallibrary.org
Phase-contrast imaging is one of the standard X-ray imaging methods at synchrotron
beamlines and has already proven to be beneficial for soft-tissue visualization. However …

[HTML][HTML] Multiscale three-dimensional imaging of intact human organs down to the cellular scale using hierarchical phase-contrast tomography.

C Walsh, P Tafforeau, WL Wagner, DJ Jafree, A Bellier… - biorxiv, 2021 - ncbi.nlm.nih.gov
Human organs are complex, three-dimensional and multiscale systems. Spatially mapping
the human body down through its hierarchy, from entire organs to their individual functional …