Adenosine and inflammation: here, there and everywhere

S Pasquini, C Contri, PA Borea, F Vincenzi… - International journal of …, 2021 - mdpi.com
Adenosine is a ubiquitous endogenous modulator with the main function of maintaining
cellular and tissue homeostasis in pathological and stress conditions. It exerts its effect …

Mechanisms of pulmonary hypertension in acute respiratory distress syndrome (ARDS)

L Revercomb, A Hanmandlu, N Wareing… - Frontiers in Molecular …, 2021 - frontiersin.org
Background: Acute respiratory distress syndrome (ARDS) is a severe and often fatal
disease. The causes that lead to ARDS are multiple and include inhalation of salt water …

Idiopathic pulmonary fibrosis and pulmonary hypertension: Heracles meets the Hydra

K Rajagopal, AJ Bryant, S Sahay… - British journal of …, 2021 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease where the additional presence of
pulmonary hypertension (PH) reduces survival. In particular, the presence of coexistent …

The Third Man: DNA sensing as espionage in pulmonary vascular health and disease

AJ Bryant, A Pham, H Gogoi, CR Mitchell… - Pulmonary …, 2021 - journals.sagepub.com
For as long as nucleic acids have been utilized to vertically and horizontally transfer genetic
material, living organisms have had to develop methods of recognizing cytosolic DNA as …

Co-inhibition of CD73 and ADORA2B improves long-term cigarette smoke induced lung injury

Z Tian, J Dixon, X Guo, B Deal, Q Liao, Y Zhou… - Frontiers in …, 2021 - frontiersin.org
Adenosine (ADO) involvement in lung injury depends on the activation of its receptors. The
ADO A2A receptor (ADORA2A) and A2B receptor (ADORA2B) are best described to have …