Fibrosis is characterized by an abnormal accumulation of extracellular matrix (ECM)
constituents in the liver parenchyma that lead to hepatic cirrhosis. After liver injury, the …

Exaggerated oxidative stress and hyper-inflammation are essential features of
oxidative/inflammatory diseases. Simultaneously, both processes may be the cause or …

The mycotoxin ochratoxin A (OTA) is a widespread contaminant in human and animal food
products. Previous studies in rats revealed that melatonin (Mel) exhibits a preventive effect …

Melatonin pleiotropically regulates physiological events and has a putative regulatory role in
the circadian clock desynchrony‐mediated Non‐alcoholic fatty liver disease (NAFLD). In this …

Glutamine is essential for maintaining the TCA cycle in cancer cells yet they undergo
glutamine starvation in the core of tumors. Cancer stem cells (CSCs), responsible for tumor …

Black mulberry (Morus nigra L.) has shown health benefits against metabolic disorders.
Lipotoxicity is considered as a potentially cause of metabolic syndrome, and there is no …

Purpose AQP5−/− mice spontaneously exhibit dry eye symptoms. The purpose of this study
was to assess the endoplasmic reticulum (ER) stress-mediated inflammation generated by a …

Background Upon liver injury, quiescent hepatic stellate cells (qHSCs), reside in the
perisinusoidal space, phenotypically transdifferentiate into myofibroblast-like cells (MFBs) …

Microglial apoptosis is associated with neuroinflammation and no effective strategies are
currently available to protect microglia against inflammation-induced apoptosis. Mouse …

Carotid artery stenosis (CAS) is an atherosclerotic disease characterized by a narrowing of
the artery lumen and a high risk of ischemic stroke. Risk factors of atherosclerosis, including …