[HTML][HTML] Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus

S Zocher, RW Overall, M Lesche, A Dahl… - Nature …, 2021 - nature.com
The decline of brain function during aging is associated with epigenetic changes, including
DNA methylation. Lifestyle interventions can improve brain function during aging, but their …

[HTML][HTML] Environmental enrichment induces epigenomic and genome organization changes relevant for cognition

S Espeso-Gil, AZ Holik, S Bonnin, S Jhanwar… - Frontiers in Molecular …, 2021 - frontiersin.org
In early development, the environment triggers mnemonic epigenomic programs resulting in
memory and learning experiences to confer cognitive phenotypes into adulthood. To …

Intergenerational influence of paternal physical activity on the offspring's brain: A systematic review and meta‐analysis

P Goli, M Yazdi, P Poursafa… - International Journal of …, 2021 - Wiley Online Library
Background It is well established that parents can influence their offspring's
neurodevelopment. It is shown that paternal environment and lifestyle is beneficial for the …

[HTML][HTML] An all-to-all approach to the identification of sequence-specific readers for epigenetic DNA modifications on cytosine

G Song, G Wang, X Luo, Y Cheng, Q Song… - Nature …, 2021 - nature.com
Epigenetic modifications of DNA play important roles in many biological processes.
Identifying readers of these epigenetic marks is a critical step towards understanding the …

[HTML][HTML] Early enriched environment prevents epigenetic p11 gene changes induced by adulthood stress in mice

MK Seo, AJ Choi, DH Seog, JG Lee… - International Journal of …, 2021 - mdpi.com
Positive experiences in early life may improve the capacity to cope with adulthood stress
through epigenetic modification. We investigated whether an enriched environment (EE) in …

Perinatal protein malnutrition results in genome-wide disruptions of 5-hydroxymethylcytosine at regions that can be restored to control levels by an enriched …

CD Alberca, LA Papale, A Madrid, O Gianatiempo… - Epigenetics, 2021 - Taylor & Francis
Maternal malnutrition remains one of the major adversities affecting brain development and
long-term mental health outcomes, increasing the risk to develop anxiety and depressive …

[PDF][PDF] Mecanismos moleculares asociados a las consecuencias comportamentales de la malnutrición proteica perinatal: estrategias de reversión

CDA Doto - 2021 - bibliotecadigital.exactas.uba.ar
Experimentar situaciones de adversidad durante los períodos críticos del desarrollo del
cerebro puede tener consecuencias deletéreas sobre el sistema nervioso central. En efecto …