Chloroquine (CQ) and hydroxychloroquine (HCQ) are the most common drugs used to
relieve acute and chronic inflammatory diseases. In this article, we present a review about …

Multi-drug resistance (MDR) is a leading cause of cancer-related death, and it continues to
be a major barrier to cancer treatment. The tumour microenvironment (TME) has proven to …

The widespread appearance of drug tolerance and the low efficiency of single treatment
have severely affected the survival time of the patients with colorectal cancer. Exploring new …

Cancer is a complex devastating disease with enormous treatment challenges, including
chemo-and radiotherapeutic resistance. Combination therapy demonstrated a promising …

Autophagy is a constitutive process that degrades, recycles and clears damaged proteins or
organelles, yet, despite activation of this pathway, abnormal proteins accumulate in neurons …

The problem of drug resistance in cancer patients has been well in mind from the beginning
of modern medicine and oncology treatments with the so called conventional cytotoxic …

Aurora B is a pivotal cell cycle regulator where errors in its function results in polyploidy,
genetic instability, and tumorigenesis. It is overexpressed in many cancers, consequently …

Objective: Autophagy influences a wide range of physiological and pathological processes
in the human body. In this study, we aimed to investigate the role of autophagy in early-onset …

The indiscriminate consumption of antimalarials against coronavirus disease‐2019
emphasizes the longstanding clinical weapons of medicines. In this work, we conducted a …