The safety of JAK-1 inhibitors

B Clarke, M Yates, M Adas, K Bechman… - Rheumatology, 2021 - academic.oup.com
As efficacy and safety data emerge, differences between JAK inhibitor subclasses are
appearing. JAK1 selective drugs, upadacitinib and filgotinib, have broadly come with the …

[HTML][HTML] Epidemiology of marginal zone lymphoma

JR Cerhan, TM Habermann - Annals of lymphoma, 2021 - ncbi.nlm.nih.gov
In 2016 there were an estimated 7,460 newly diagnosed patients with marginal zone
lymphoma (MZL) in the US, which comprised 7% of all mature non-Hodgkin lymphomas …

Genetic predisposition to lymphomas: Overview of rare syndromes and inherited familial variants

B Szmyd, W Mlynarski, A Pastorczak - Mutation Research/Reviews in …, 2021 - Elsevier
Approximately 10% of malignancies occur in carriers of germline mutations predisposing to
cancer. A high risk of developing lymphomas has been noted in many primary …

[HTML][HTML] Intake of fruits and vegetables by pesticide residue status in relation to cancer risk

H Sandoval-Insausti, YH Chiu, DH Lee, S Wang… - Environment …, 2021 - Elsevier
Background Conventionally grown fruits and vegetables (FVs) are the main source of
general population exposure to pesticide residues. Objective To evaluate the relation of …

The bidirectional increased risk of B-cell lymphoma and T-cell lymphoma

D Chihara, GM Dores, CR Flowers… - Blood, The Journal of …, 2021 - ashpublications.org
Lymphoma survivors have a significantly higher risk of developing second primary
lymphoma than the general population; however, bidirectional risks of developing B-and T …

Occupational insecticide exposure and risk of n on‐Hodgkin lymphoma: A pooled c ase‐control study from the InterLymph Consortium

AJ De Roos, LH Schinasi, L Miligi… - … journal of cancer, 2021 - Wiley Online Library
Evidence for the human health effects of pesticides is needed to inform risk assessment. We
studied the relationship between occupational insecticide use and risk of non‐Hodgkin …

Tumor necrosis factor inhibitors and the risk of cancer among older Americans with rheumatoid arthritis

ME D'Arcy, DC Beachler, RM Pfeiffer, JR Curtis… - … Biomarkers & Prevention, 2021 - AACR
Background: TNF inhibitors (TNFi) effectively treat rheumatoid arthritis but may increase
patient risk of some malignancies, particularly lymphomas or skin cancers. Methods: We …

Risk of rare cancers among solid organ transplant recipients

ME D'Arcy, D Castenson, CF Lynch… - JNCI: Journal of the …, 2021 - academic.oup.com
Background Immunosuppressed solid organ transplant recipients (SOTRs) have elevated
rates of certain rare cancers caused by viruses. Evaluating risk of rare cancers among …

[HTML][HTML] Alterations of 5-hydroxymethylation in circulating cell-free DNA reflect molecular distinctions of subtypes of non-Hodgkin lymphoma

BCH Chiu, C Chen, Q You, R Chiu… - NPJ genomic …, 2021 - nature.com
Abstract The 5-methylcytosines (5mC) have been implicated in the pathogenesis of diffuse
large B-cell lymphoma (DLBCL) and follicular lymphoma (FL). However, the role of 5 …

[HTML][HTML] Risk of non-Hodgkin lymphoma in breast cancer survivors: a nationwide cohort study

D Kang, SE Yoon, D Shin, J Lee, YS Hong… - Blood cancer …, 2021 - nature.com
Several studies have suggested that estrogens have a protective function against
lymphomagenesis. The treatment of breast cancer is driven by subtype classification, and …