Objective To assess the effectiveness and safety of different preparations and doses of non-
steroidal anti-inflammatory drugs (NSAIDs), opioids, and paracetamol for knee and hip …

Objectives To investigate changes in analgesic use before and after supervised exercise
therapy and patient education in patients with knee or hip osteoarthritis (OA). Methods We …

Background It is crucial to identify patients at highest risk for opioid use disorder (OUD) and
to address challenges in reducing opioid use. Reported nonsteroidal anti-inflammatory drug …

Background The DSM-5 diagnostic criteria for Prescription Opioid-Use Disorder (POUD)
have undergone some significant changes. One of the most controversial changes has been …

Objective Describe trends and patterns in long-term opioid prescriptions among adults with
musculoskeletal conditions (MSK). Design Interrupted time-series analysis based on an …

Background It is common for adults with opioid use disorder (OUD) to misuse additional
substances, and these individuals may be particularly at risk for adverse events, including …

BACKGROUND CONTEXT Despite increased awareness of the ongoing opioid epidemic,
opioid and benzodiazepine use remain high after spine surgery. In particular, long-term co …

Objective: Receipt of concurrent psychotropic prescription medications from both US
Department of Veterans Affairs (VA) and non-VA healthcare providers may increase risk of …

Objective While opioids are known to cause unintended adverse effects, they are being
utilized by a number of patients with osteoarthritis (OA). The aim of this study was to evaluate …

Background Widespread use of prescription opioids is associated with adverse outcomes.
Objective To identify factors associated with adverse health outcomes and health care use …