INTRODUCTION All body cells rely on blood vessels (BVs) for the provision of oxygen and
other blood-borne substances and, in certain settings, also for the provision of endothelial …

Background A chronic imbalance of energy intake and energy expenditure results in excess
fat storage. The obesity often caused by this overweight is detrimental to the health of …

Uncertainty exists as to whether the glucose-dependent insulinotropic polypeptide receptor
(GIPR) should be activated or inhibited for the treatment of obesity. Gipr was recently …

Heart failure with preserved ejection fraction (HFpEF) is a highly prevalent and intractable
form of cardiac decompensation commonly associated with diastolic dysfunction. Here, we …

How to adjust metabolic rate (MR) in mice that differ in body mass and composition
continues to lead to controversies. Here, the challenges that reside in the analysis of mouse …

White to brown/beige adipocytes conversion is a possible therapeutic strategy to tackle the
current obesity epidemics. While mitochondria are key for energy dissipation in brown fat, it …

Dysregulation of energy homeostasis in amyotrophic lateral s... : Current Opinion in Neurology
Dysregulation of energy homeostasis in amyotrophic lateral sclerosis : Current Opinion in …

Overnutrition causes obesity, a global health problem without any effective therapy. Obesity
is characterized by low-grade inflammation, which predisposes individuals to metabolic …

Objective The vagus nerve provides a direct line of communication between the gut and the
brain for proper regulation of energy balance and glucose homeostasis. Short-chain fatty …

Maternal obesity (MO) predisposes offspring to obesity and metabolic disorders but little is
known about the contribution of offspring brown adipose tissue (BAT). We find that MO …