[HTML][HTML] Glioblastoma Multiforme—A Look at the Past and a Glance at the Future

JL King, SR Benhabbour - Pharmaceutics, 2021 - mdpi.com
Gliomas are the most common type of brain tumor that occur in adults and children.
Glioblastoma multiforme (GBM) is the most common, aggressive form of brain cancer in …

[HTML][HTML] Cell-based therapy for the treatment of glioblastoma: an update from preclinical to clinical studies

N Attia, M Mashal, S Pemminati, A Omole… - Cells, 2021 - mdpi.com
Glioblastoma (GB), an aggressive primary tumor of the central nervous system, represents
about 60% of all adult primary brain tumors. It is notorious for its extremely low (~ 5%) 5-year …

Intravenously infused stem cells for cancer treatment

AR Mercer-Smith, IA Findlay, HN Bomba… - Stem cell reviews and …, 2021 - Springer
Despite the recent influx of immunotherapies and small molecule drugs to treat tumors,
cancer remains a leading cause of death in the United States, in large part due to the …

Cytotoxic Engineered Induced Neural Stem Cells as an Intravenous Therapy for Primary Non–Small Cell Lung Cancer and Triple-Negative Breast Cancer

AR Mercer-Smith, W Jiang, JR Bago, A Valdivia… - Molecular cancer …, 2021 - AACR
Converting human fibroblasts into personalized induced neural stem cells (hiNSC) that
actively seek out tumors and deliver cytotoxic agents is a promising approach for treating …

Developing Induced Neural Stem Cell Therapy to Treat Triple-Negative Breast Cancer and Brain Metastases

W Jiang - 2021 - search.proquest.com
Triple-negative breast cancer (TNBC) is the most deadly subtype of breast cancer, with a
high incidence of brain metastasis. With the absence of targetable molecules on the cell …

Tumor-Homing Cytotoxic Induced Neural Stem Cells for the Treatment of Primary and Metastatic Non-Small Cell Lung Cancer

AR Mercer-Smith - 2021 - search.proquest.com
Lung cancer accounts for more deaths than any other type of cancer. 44% of all brain
metastases are due to non-small cell lung cancer (NSCLC), and the median survival for …