Apicomplexans are a group of pathogenic protists that cause various diseases in humans
and animals that cause economic losses worldwide. These unicellular eukaryotes are …

Obligate intracellular malaria parasites reside within a vacuolar compartment generated
during invasion which is the principal interface between pathogen and host. To subvert their …

Gametocytogenesis, the process by which malaria parasites produce sexual forms that can
infect mosquitoes, is essential for the transmission of malaria. A transcriptional switch of the …

Plasmodium falciparum VAR2CSA binds to chondroitin sulfate A (CSA) on the surface of the
syncytiotrophoblast during placental malaria. This interaction facilitates placental …

824-Pos Surface Area-to-Volume Ratio, not Cellular Viscoelasticity is the Major Determinant
of Red Blood Cell Traversal through Small Channels Arman Namvar1, 2, Adam Blanch2 …

Plasmodium malaria parasites are obligate intracellular protozoans that use a unique form
of locomotion, termed gliding motility, to move through host tissues and invade cells. The …

In both sickle cell disease and malaria, red blood cells (RBCs) are phagocytosed in the
spleen, but receptor-ligand pairs mediating uptake have not been identified. Here, we report …

Malaria parasites use the RhopH complex for erythrocyte invasion and channel-mediated
nutrient uptake. As the member proteins are unique to Plasmodium spp., how they interact …

Some Plasmodium falciparum repetitive interspersed families of polypeptides (RIFINs)—
variant surface antigens that are expressed on infected erythrocytes—bind to the inhibitory …

The last malaria parasite standing will display effective adaptations to selective forces. While
substantial progress has been made in reducing malaria mortality, eradication will require …