[HTML][HTML] EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood

M Weller, M van den Bent, M Preusser… - Nature reviews Clinical …, 2021 - nature.com
In response to major changes in diagnostic algorithms and the publication of mature results
from various large clinical trials, the European Association of Neuro-Oncology (EANO) …

[HTML][HTML] Prognostic and predictive biomarkers in gliomas

P Śledzińska, MG Bebyn, J Furtak… - International journal of …, 2021 - mdpi.com
Gliomas are the most common central nervous system tumors. New technologies, including
genetic research and advanced statistical methods, revolutionize the therapeutic approach …

The rsna-asnr-miccai brats 2021 benchmark on brain tumor segmentation and radiogenomic classification

U Baid, S Ghodasara, S Mohan, M Bilello… - arXiv preprint arXiv …, 2021 - arxiv.org
The BraTS 2021 challenge celebrates its 10th anniversary and is jointly organized by the
Radiological Society of North America (RSNA), the American Society of Neuroradiology …

Clinical practice guidelines for the management of adult diffuse gliomas

T Jiang, DH Nam, Z Ram, W Poon, J Wang… - Cancer letters, 2021 - Elsevier
To follow the revision of the fourth edition of WHO classification and the recent progress on
the management of diffuse gliomas, the joint guideline committee of Chinese Glioma …

Integrated molecular-morphologic meningioma classification: a multicenter retrospective analysis, retrospectively and prospectively validated

SLN Maas, D Stichel, T Hielscher, P Sievers… - Journal of clinical …, 2021 - ascopubs.org
PURPOSE Meningiomas are the most frequent primary intracranial tumors. Patient outcome
varies widely from benign to highly aggressive, ultimately fatal courses. Reliable …

[HTML][HTML] Role of glioblastoma stem cells in cancer therapeutic resistance: A perspective on antineoplastic agents from natural sources and chemical derivatives

ALV Alves, INF Gomes, AC Carloni, MN Rosa… - Stem Cell Research & …, 2021 - Springer
Glioblastoma (GBM) is the highest-grade form of glioma, as well as one of the most
aggressive types of cancer, exhibiting rapid cellular growth and highly invasive behavior …

[HTML][HTML] Hypoxia: the cornerstone of glioblastoma

M Domènech, A Hernández, A Plaja… - International journal of …, 2021 - mdpi.com
Glioblastoma is the most aggressive form of brain tumor in adults and is characterized by the
presence of hypervascularization and necrosis, both caused by a hypoxic …

The 2021 WHO classification of tumors of the central nervous system: a summary

DN Louis, A Perry, P Wesseling, DJ Brat… - Neuro …, 2021 - academic.oup.com
The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS),
published in 2021, is the sixth version of the international standard for the classification of …

The immune landscape of common CNS malignancies: implications for immunotherapy

M Ott, RM Prins, AB Heimberger - Nature Reviews Clinical Oncology, 2021 - nature.com
Immunotherapy has enabled remarkable therapeutic responses across cancers of various
lineages, albeit with some notable exceptions such as glioblastoma. Several previous …

[HTML][HTML] Tumor heterogeneity in glioblastomas: from light microscopy to molecular pathology

AP Becker, BE Sells, SJ Haque, A Chakravarti - Cancers, 2021 - mdpi.com
Simple Summary Glioblastomas (GBMs) are the most frequent and aggressive malignant
tumors arising in the human brain. One of the main reasons for GBM aggressiveness is its …