High‐throughput metagenomics for identification of pathogens in the clinical settings
N Li, Q Cai, Q Miao, Z Song, Y Fang, B Hu - Small methods, 2021 - Wiley Online Library
The application of sequencing technology is shifting from research to clinical laboratories
owing to rapid technological developments and substantially reduced costs. However …
owing to rapid technological developments and substantially reduced costs. However …
[HTML][HTML] High throughput sequencing for the detection and characterization of RNA viruses
This review aims to assess and recommend approaches for targeted and agnostic High
Throughput Sequencing of RNA viruses in a variety of sample matrices. HTS also referred to …
Throughput Sequencing of RNA viruses in a variety of sample matrices. HTS also referred to …
[HTML][HTML] Re-emergence of enterovirus D68 in Europe after easing the COVID-19 lockdown, September 2021
We report a rapid increase in enterovirus D68 (EV-D68) infections, with 139 cases reported
from eight European countries between 31 July and 14 October 2021. This upsurge is in line …
from eight European countries between 31 July and 14 October 2021. This upsurge is in line …
Undetectable viral RNA in oocytes from SARS-CoV-2 positive women
M Barragan, JJ Guillén, N Martin-Palomino… - Human …, 2021 - academic.oup.com
A central concern for the safe provision of ART during the current coronavirus disease 2019
(COVID-19) pandemic is the possibility of vertical transmission of severe acute respiratory …
(COVID-19) pandemic is the possibility of vertical transmission of severe acute respiratory …
Pseudomonas aeruginosa: a clinical and genomics update
AC Pelegrin, M Palmieri, C Mirande… - FEMS Microbiology …, 2021 - academic.oup.com
Antimicrobial resistance (AMR) has become a global medical priority that needs urgent
resolution. Pseudomonas aeruginosa is a versatile, adaptable bacterial species with …
resolution. Pseudomonas aeruginosa is a versatile, adaptable bacterial species with …
Future potential of metagenomics in microbiology laboratories
Rapid and sensitive diagnostic strategies are necessary for patient care and public health.
Most of the current conventional microbiological assays detect only a restricted panel of …
Most of the current conventional microbiological assays detect only a restricted panel of …
[HTML][HTML] A theoretical and generalized approach for the assessment of the sample-specific limit of detection for clinical metagenomics
A Ebinger, S Fischer, D Hoeper - Computational and structural …, 2021 - Elsevier
Metagenomics is a powerful tool to identify novel or unexpected pathogens, since it is
generic and relatively unbiased. The limit of detection (LOD) is a critical parameter for the …
generic and relatively unbiased. The limit of detection (LOD) is a critical parameter for the …
[HTML][HTML] HTS-based diagnostics of sugarcane viruses: Seasonal variation and its implications for accurate detection
Rapid global germplasm trade has increased concern about the spread of plant pathogens
and pests across borders that could become established, affecting agriculture and …
and pests across borders that could become established, affecting agriculture and …
[HTML][HTML] Deep impact of random amplification and library construction methods on viral metagenomics results
Clinical metagenomics is a broad-range agnostic detection method of pathogens, including
novel microorganisms. A major limit is the low pathogen load compared to the high …
novel microorganisms. A major limit is the low pathogen load compared to the high …
[HTML][HTML] Metagenomic next-generation sequencing (mNGS) for diagnosis of invasive fungal infectious diseases: a narrative review
N Song, X Li, W Liu - Journal of Laboratory and Precision …, 2021 - jlpm.amegroups.org
Invasive fungal diseases (IFDs) remain important causes of high morbidity and mortality in
many immunosuppressed patients. Accurate etiology diagnosis coupled with subsequent …
many immunosuppressed patients. Accurate etiology diagnosis coupled with subsequent …