[HTML][HTML] α-Synuclein A53T binds to transcriptional adapter 2-alpha and blocks histone H3 acetylation
JY Lee, H Kim, A Jo, R Khang, CH Park… - International Journal of …, 2021 - mdpi.com
α-Synuclein (α-syn) is a hallmark amyloidogenic protein component of Lewy bodies in
dopaminergic neurons affected by Parkinson's disease (PD). Despite the multi-faceted gene …
dopaminergic neurons affected by Parkinson's disease (PD). Despite the multi-faceted gene …
[HTML][HTML] Untangling the interaction of α-synuclein with DNA i-motifs and hairpins by volume-sensitive single-molecule FRET spectroscopy
SK Mukherjee, JM Knop, R Oliva, S Möbitz… - RSC Chemical …, 2021 - pubs.rsc.org
The intrinsically disordered protein α-synuclein causes Parkinson's disease by forming toxic
oligomeric aggregates inside neurons. Single-molecule FRET experiments revealed …
oligomeric aggregates inside neurons. Single-molecule FRET experiments revealed …