The occurrence order and cross-talk of different tRNA modifications

J Li, WY Zhu, WQ Yang, CT Li, RJ Liu - Science China Life Sciences, 2021 - Springer
Chemical modifications expand the composition of RNA molecules from four standard
nucleosides to over 160 modified nucleosides, which greatly increase the complexity and …

[HTML][HTML] Post-transcriptional modifications of conserved nucleotides in the T-loop of tRNA: a tale of functional convergent evolution

M Roovers, L Droogmans, H Grosjean - Genes, 2021 - mdpi.com
The high conservation of nucleotides of the T-loop, including their chemical identity, are
hallmarks of tRNAs from organisms belonging to the three Domains of Life. These structural …

THUMPD3–TRMT112 is am2G methyltransferase working on a broad range of tRNA substrates

WQ Yang, QP Xiong, JY Ge, H Li, WY Zhu… - Nucleic acids …, 2021 - academic.oup.com
Post-transcriptional modifications affect tRNA biology and are closely associated with
human diseases. However, progress on the functional analysis of tRNA modifications in …

[HTML][HTML] Deciphering the Role of Residues Involved in Disorder-To-Order Transition Regions in Archaeal tRNA Methyltransferase 5

A Srivastava, D Yesudhas, S Ahmad, MM Gromiha - Genes, 2021 - mdpi.com
tRNA methyltransferase 5 (Trm5) enzyme is an S-adenosyl methionine (AdoMet)-dependent
methyltransferase which methylates the G37 nucleotide at the N1 atom of the tRNA. The free …

[PDF][PDF] Post-Transcriptional Modifications of Conserved Nucleotides in the T-Loop of tRNA: A Tale of Functional Convergent Evolution. Genes 2021, 12, 140

M Roovers, L Droogmans, H Grosjean - 2021 - pdfs.semanticscholar.org
The high conservation of nucleotides of the T-loop, including their chemical identity, are
hallmarks of tRNAs from organisms belonging to the three Domains of Life. These structural …

[PDF][PDF] Deciphering the Role of Residues Involved in Disorder-To-Order Transition Regions in Archaeal tRNA Methyltransferase 5. Genes 2021, 12, 399

A Srivastava, D Yesudhas, S Ahmad, MM Gromiha - 2021 - pdfs.semanticscholar.org
tRNA methyltransferase 5 (Trm5) enzyme is an S-adenosyl methionine (AdoMet)-dependent
methyltransferase which methylates the G37 nucleotide at the N1 atom of the tRNA. The free …