[HTML][HTML] Immunological mechanisms of vaccine-induced protection against COVID-19 in humans

M Sadarangani, A Marchant… - Nature Reviews …, 2021 - nature.com
Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …

[HTML][HTML] COVID-19: a review on the novel coronavirus disease evolution, transmission, detection, control and prevention

A Sharma, I Ahmad Farouk, SK Lal - Viruses, 2021 - mdpi.com
Three major outbreaks of the coronavirus, a zoonotic virus known to cause respiratory
disease, have been reported since 2002, including SARS-CoV, MERS-CoV and the most …

RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental …

SK Burley, C Bhikadiya, C Bi, S Bittrich… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB
PDB), the US data center for the global PDB archive and a founding member of the …

[HTML][HTML] Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy

Q Zhang, R Xiang, S Huo, Y Zhou, S Jiang… - Signal transduction and …, 2021 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …

[HTML][HTML] SARS-CoV-2 accessory proteins in viral pathogenesis: knowns and unknowns

N Redondo, S Zaldívar-López, JJ Garrido… - Frontiers in …, 2021 - frontiersin.org
There are still many unanswered questions concerning viral SARS-CoV-2 pathogenesis in
COVID-19. Accessory proteins in SARS-CoV-2 consist of eleven viral proteins whose roles …

[HTML][HTML] Coronavirus biology and replication: implications for SARS-CoV-2

P V'kovski, A Kratzel, S Steiner, H Stalder… - Nature Reviews …, 2021 - nature.com
The SARS-CoV-2 pandemic and its unprecedented global societal and economic disruptive
impact has marked the third zoonotic introduction of a highly pathogenic coronavirus into the …

[HTML][HTML] Deciphering cell–cell interactions and communication from gene expression

E Armingol, A Officer, O Harismendy… - Nature Reviews …, 2021 - nature.com
Cell–cell interactions orchestrate organismal development, homeostasis and single-cell
functions. When cells do not properly interact or improperly decode molecular messages …

The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions

R Oughtred, J Rust, C Chang, BJ Breitkreutz… - Protein …, 2021 - Wiley Online Library
Abstract The BioGRID (Biological General Repository for Interaction Datasets, thebiogrid.
org) is an open‐access database resource that houses manually curated protein and …

[HTML][HTML] COVID-19 and liver disease: mechanistic and clinical perspectives

T Marjot, GJ Webb, AS Barritt IV, AM Moon… - Nature reviews …, 2021 - nature.com
Our understanding of the hepatic consequences of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection and its resultant coronavirus disease 2019 (COVID …

COVID-19 and cardiovascular disease: from bench to bedside

MK Chung, DA Zidar, MR Bristow, SJ Cameron… - Circulation …, 2021 - Am Heart Assoc
A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential
consequences on the cardiovascular health of millions of people who survive infection …