Dilated cardiomyopathy (DCM) is an umbrella term entailing a wide variety of genetic and
non-genetic etiologies, leading to left ventricular systolic dysfunction and dilatation, not …

Germline DDX41 variants in myeloid neoplasms (MNs) are not uncommon, and we explored
the prevalence and characterized the clinical and pathologic features in a cohort of 3132 …

Cardiomyopathies (CMPs) are myocardial diseases in which the heart muscle is structurally
and functionally abnormal in the absence of coronary artery disease, hypertension, valvular …

Simple Summary Heart disease is a leading cause of death for both humans and dogs.
Inherited heart diseases, including dilated cardiomyopathy (DCM), account for a proportion …

Background According to patterns of inheritance and incomplete penetrance, fewer than half
of relatives to dilated cardiomyopathy probands will develop disease. Objectives The …

RBM20 cardiomyopathy is an arrhythmogenic form of dilated cardiomyopathy caused by
mutations in the splicing factor RBM20. A recent study found a more severe phenotype in …

Abstract Purpose of Review Heart failure (HF) is a significant cause of morbidity and
mortality worldwide with unique phenotypes in men and women. Cardiomyopathy is a …

Cardiac arrhythmias (CAs) are generally caused by disruption of the cardiac conduction
system; interleukin-2 (IL-2) is a key player in the pathological process of CAs. This study …

Lamin A/C (LMNA) mutations cause familial dilated cardiomyopathy (DCM) with autosomal
dominant inheritance and variable phenotypic expression, 1 such as early-onset …

Dilated cardiomyopathy (DCM) is a progressive myocardial disease that leads to dilatation
of cardiac ventricles, reduced contractile force, and a high risk of sudden cardiac death. The …