[HTML][HTML] The role of imaging biomarkers to guide pharmacological interventions targeting tumor hypoxia
B Gallez - Frontiers in pharmacology, 2022 - frontiersin.org
Hypoxia is a common feature of solid tumors that contributes to angiogenesis, invasiveness,
metastasis, altered metabolism and genomic instability. As hypoxia is a major actor in tumor …
metastasis, altered metabolism and genomic instability. As hypoxia is a major actor in tumor …
Hypoxia imaging as a guide for hypoxia-modulated and hypoxia-activated therapy
JR Brender, Y Saida, N Devasahayam… - Antioxidants & Redox …, 2022 - liebertpub.com
Significance: Oxygen imaging techniques, which can probe the spatiotemporal
heterogeneity of tumor oxygenation, could be of significant clinical utility in radiation …
heterogeneity of tumor oxygenation, could be of significant clinical utility in radiation …
[HTML][HTML] Increasing oxygen tension in tumor tissue using ultrasound sensitive O2 microbubbles
A Drzał, A Delalande, G Dziurman, M Fournié… - Free Radical Biology …, 2022 - Elsevier
Low tissue oxygenation significantly impairs the effectiveness of cancer therapy and
promotes a more aggressive phenotype. Many strategies to improve tissue oxygenation …
promotes a more aggressive phenotype. Many strategies to improve tissue oxygenation …
[HTML][HTML] The Challenges of O2 Detection in Biological Fluids: Classical Methods and Translation to Clinical Applications
V Marassi, S Giordani, A Kurevija, E Panetta… - International Journal of …, 2022 - mdpi.com
Dissolved oxygen (DO) is deeply involved in preserving the life of cellular tissues and
human beings due to its key role in cellular metabolism: its alterations may reflect important …
human beings due to its key role in cellular metabolism: its alterations may reflect important …
Spatiotemporal imaging of redox status using in vivo dynamic nuclear polarization magnetic resonance imaging system for early monitoring of response to radiation …
N Koyasu, F Hyodo, R Iwasaki, H Eto… - Free Radical Biology …, 2022 - Elsevier
In general, the effectiveness of radiation treatment is evaluated through the observation of
morphological changes with computed tomography (CT) or magnetic resonance imaging …
morphological changes with computed tomography (CT) or magnetic resonance imaging …
[HTML][HTML] EPR Investigations to Study the Impact of Mito-Metformin on the Mitochondrial Function of Prostate Cancer Cells
Background: Mito-metformin10 (MM10), synthesized by attaching a triphenylphosphonium
cationic moiety via a 10-carbon aliphatic side chain to metformin, is a mitochondria-targeted …
cationic moiety via a 10-carbon aliphatic side chain to metformin, is a mitochondria-targeted …