[HTML][HTML] Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer

H Zhou, L Zhu, J Song, G Wang, P Li, W Li, P Luo… - Molecular cancer, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …

Using circulating tumor DNA in colorectal cancer: current and evolving practices

M Malla, JM Loree, PM Kasi, AR Parikh - Journal of Clinical Oncology, 2022 - ascopubs.org
There exists a tremendous opportunity in identifying and determining the appropriate
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …

[HTML][HTML] ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group

J Pascual, G Attard, FC Bidard, G Curigliano… - Annals of …, 2022 - Elsevier
Circulating tumour DNA (ctDNA) assays conducted on plasma are rapidly developing a
strong evidence base for use in patients with cancer. The European Society for Medical …

The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of colon cancer

JD Vogel, SI Felder, AR Bhama… - Diseases of the Colon …, 2022 - journals.lww.com
METHODS This guideline is based on the previous colon cancer parameter published in
2017. 10 Compared with 2017, this guideline has 11 new, 10 updated, and 2 excluded …

Circulating tumor DNA in stage III colorectal cancer, beyond minimal residual disease detection, toward assessment of adjuvant therapy efficacy and clinical behavior …

TV Henriksen, N Tarazona, A Frydendahl… - Clinical Cancer …, 2022 - AACR
Purpose: Sensitive methods for risk stratification, monitoring therapeutic efficacy, and early
relapse detection may have a major impact on treatment decisions and patient management …

Circulating tumor DNA minimal residual disease detection of non–small-cell lung cancer treated with curative intent

B Pellini, AA Chaudhuri - Journal of Clinical Oncology, 2022 - ascopubs.org
Circulating tumor DNA (ctDNA) minimal residual disease (MRD) is a powerful biomarker
with the potential to improve survival outcomes for non–small-cell lung cancer (NSCLC) …

A comprehensive framework for early-onset colorectal cancer research

C Eng, AA Jacome, R Agarwal, MH Hayat… - The Lancet …, 2022 - thelancet.com
Sporadic colorectal cancer has traditionally been viewed as a malignancy of older
individuals. However, as the global prevalence of the disease diagnosed in younger …

[HTML][HTML] Predictive biomarkers of colon cancer immunotherapy: Present and future

W Hou, C Yi, H Zhu - Frontiers in immunology, 2022 - frontiersin.org
Immunotherapy has revolutionized colon cancer treatment. Immune checkpoint inhibitors
(ICIs) have shown clinical benefits for colon cancer patients, especially those with high …

[HTML][HTML] Integrating circulating-free DNA (cfDNA) analysis into clinical practice: opportunities and challenges

M Garcia-Pardo, M Makarem, JJN Li, D Kelly… - British Journal of …, 2022 - nature.com
In the current era of precision medicine, the identification of genomic alterations has
revolutionised the management of patients with solid tumours. Recent advances in the …

[HTML][HTML] Liquid biopsies to monitor and direct cancer treatment in colorectal cancer

G Mauri, PP Vitiello, A Sogari, G Crisafulli… - British Journal of …, 2022 - nature.com
Colorectal cancer (CRC) is one of the most prevalent and deadly cancers worldwide.
Despite recent improvements in treatment and prevention, most of the current therapeutic …