There is an urgent need for exploring new actionable targets other than androgen receptor
to improve outcome from lethal castration-resistant prostate cancer. Tumor metabolism has …

MVI has significant clinical value for treatment selection and prognosis evaluation in
hepatocellular carcinoma (HCC). We aimed to construct a model based on MVI-Related …

Diabetes is directly related to the risk of breast cancer (BC) occurrence and worsened BC
prognosis. Currently, there are no specific treatments for diabetes‐associated BC. This …

Highly glycolytic cancer cells excrete lactate to maintain cellular homeostasis. Inhibiting
lactate export by pharmacological targeting of plasma membrane lactate transporters is …

Tumour metabolomics and transcriptomics co-expression network as related to biological
folate alteration and cancer malignancy remains unexplored in human non-small cell lung …

BACKGROUND: Anaplastic thyroid cancer (ATC) is an aggressive malignancy without
effective treatments. ATC cells demonstrate upregulated glycolysis (Warburg effect) …

Background/Aim: Lung cancer is the most prevalent type of cancer globally and small cell
lung cancer (SCLC) accounts for only 15% of all cases but exhibits a dismal prognosis. The …

The most common cancers of the aerodigestive tract (ADT) are non-small cell lung cancer
(NSCLC) and head and neck squamous cell carcinoma (HNSCC). The tumor stroma plays …

Ovarian cancer is a non-homogenous malignancy. High-grade serous carcinoma (HGSC) is
the most common subtype, and its drug resistance mechanisms remain unclear. Despite the …

Background: Clear cell renal cell carcinoma (ccRCC) is the most common type of renal cell
carcinomas. The Von Hippel-Lindau (VHL) tumour suppressor gene is frequently altered in …