The long-acting antiretroviral cabotegravir and rilpivirine combination has just received FDA,
EMA and Health Canada approval. This novel drug delivery approach is about to …

Introduction We see a development in the field of long-acting products to serve patients with
chronic diseases by providing benefits in adherence, efficacy, and safety of the treatment …

Ultra-long-acting integrase strand transfer inhibitors were created by screening a library of
monomeric and dimeric dolutegravir (DTG) prodrug nanoformulations. This led to an 18 …

Formulating aqueous suspensions is an attractive strategy to incorporate poorly water-
soluble drugs, where the drug release can be tailored to maintain desired release profiles of …

Monosialodihexosylganglioside (GM3)-presenting lipid-coated polymer nanoparticles (NPs)
that recapitulate the sequestration of human immunodeficiency virus-1 (HIV-1) particles in …

SHCS# 879 is an ongoing Switzerland-wide multicenter observational study conducted
within the Swiss HIV Cohort Study (SHCS) for the prospective follow-up of people living with …

Intramuscularly injectable long-acting prodrug-based microcrystals (MCs) are of particular
interest for chronic disease management. Nevertheless, current prevalently used linkers …

Abstract An “ultra” long-acting (LA) integrase strand transfer inhibitor was created by
screening a library of monomeric and dimeric dolutegravir (DTG) prodrug nanoformulations …