Mitochondrial DNA Is a Vital Driving Force in Ischemia‐Reperfusion Injury in Cardiovascular Diseases

H Liu, X Liu, J Zhou, T Li - Oxidative Medicine and Cellular …, 2022 - Wiley Online Library
According to the latest Global Burden of Disease Study, cardiovascular disease (CVD) is the
leading cause of death, and ischemic heart disease and stroke are the cause of death in …

[HTML][HTML] Gender-differences in antithrombotic therapy across the spectrum of ischemic heart disease: Time to tackle the Yentl syndrome?

R Laborante, JA Borovac, M Galli… - Frontiers in …, 2022 - frontiersin.org
The incidence and clinical presentation of ischemic heart disease (IHD), as well as
thrombotic and bleeding risks, appear to differ between genders. Compared with men …

Impact of ischaemic aetiology on the efficacy of intravenous ferric carboxymaltose in patients with iron deficiency and acute heart failure: insights from the AFFIRM …

M Metra, EA Jankowska, M Pagnesi… - European journal of …, 2022 - Wiley Online Library
Aims In AFFIRM‐AHF, intravenous ferric carboxymaltose (FCM) reduced heart failure (HF)
hospitalisations and improved quality of life versus placebo in iron‐deficient patients …

Integrated Bioinformatics and Validation of lncRNA‐Mediated ceRNA Network in Myocardial Ischemia/Reperfusion Injury

Y Han, G Jin, M Pan, Z Fang, D Lu… - Journal of Immunology …, 2022 - Wiley Online Library
Background. Myocardial ischemia/reperfusion (MI/R) injury is a common pathology in
ischemia heart disease. Long noncoding RNAs (lncRNAs) are significant regulators related …

[HTML][HTML] IP3 receptor orchestrates maladaptive vascular responses in heart failure

H Dridi, G Santulli, J Gambardella… - The Journal of …, 2022 - Am Soc Clin Investig
Patients with heart failure (HF) have augmented vascular tone, which increases cardiac
workload, impairing ventricular output and promoting further myocardial dysfunction. The …

Specific tracking of monoamine oxidase A in heart failure models by a far-red fluorescent probe with an ultra large Stokes shift

X Li, D Shi, Y Song, Y Xu, Y Gao, W Qiu, X Chen… - Chinese Chemical …, 2022 - Elsevier
Abstract Monoamine oxidase A (MAO-A) is a prominent myocardial source of reactive
oxygen species (ROS), and its expression and activity are strongly increased in failing …

[HTML][HTML] Therapeutic potential of VEGF-B in coronary heart disease and heart failure: dream or vision?

R Mallick, S Ylä-Herttuala - Cells, 2022 - mdpi.com
Coronary heart disease (CHD) is the leading cause of death around the world. Based on the
roles of vascular endothelial growth factor (VEGF) family members to regulate blood and …

[HTML][HTML] The association between ACTB methylation in peripheral blood and coronary heart disease in a case-control study

J Jin, C Zhu, J Wang, X Zhao, R Yang - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Background Coronary heart disease (CHD) brings a heavy burden to society worldwide.
Novel and minimally invasive biomarkers for the risk evaluation of CHD are urgently …

Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro

Q Wan, L Zhang, Q Zhou, Y Han, Z Li, B Li - Inflammation, 2022 - Springer
Although it is known that caffeic acid phenethyl ester (CAPE) and its derivatives could
ameliorate acute myocardial injury, their effects on chronic myocardial ischemia (CMI) were …

DJ-1 activates the AMPK/mTOR pathway by binding RACK1 to induce autophagy and protect the myocardium from ischemia/hypoxia injury

XY Zhao, JM Ren, HR Liu, TT Zhou, XY Wang… - Biochemical and …, 2022 - Elsevier
Abstract Myocardial Ischemic Injury is a serious threat to human health, and DJ-1 is involved
in cardioprotection. The research intended to explore the effects and mechanism of DJ-1 to …