Congenital adrenal hyperplasia—current insights in pathophysiology, diagnostics, and management

HL Claahsen-van der Grinten, PW Speiser… - Endocrine …, 2022 - academic.oup.com
Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting
cortisol biosynthesis. Reduced activity of an enzyme required for cortisol production leads to …

[HTML][HTML] Challenges in treatment of patients with non-classic congenital adrenal hyperplasia

BPH Adriaansen, MAM Schröder, PN Span… - Frontiers in …, 2022 - frontiersin.org
Congenital adrenal hyperplasia (CAH) due to 21α-hydroxylase deficiency (21OHD) or 11β-
hydroxylase deficiency (11OHD) are congenital conditions with affected adrenal …

[HTML][HTML] Getting pregnant with congenital adrenal hyperplasia: Assisted reproduction and pregnancy complications. A systematic review and meta-analysis

X Guo, Y Zhang, Y Yu, L Zhang, K Ullah, M Ji… - Frontiers in …, 2022 - frontiersin.org
Many patients with congenital adrenal hyperplasia (CAH) refrain from seeking pregnancy,
suffer from infertility or worry about pregnancy complications, mainly due to genitalia …

[HTML][HTML] Adrenal hyperplasias in childhood: An update

G Pitsava, CA Stratakis - Frontiers in Endocrinology, 2022 - frontiersin.org
Pediatric adrenocortical hyperplasias are rare; they usually present with Cushing syndrome
(CS); of them, isolated micronodular adrenal disease and its variant, primary pigmented …

Classical and non-classical congenital adrenal hyperplasia: What is the difference in subsequent fertility?

C Carrière, C Sarfati, I Téjédor, J Dulon… - Annales d' …, 2022 - Elsevier
Hydroxylase deficiency (21OHD) is the most common cause of congenital adrenal
hyperplasia. Increased production of adrenal-derived androgens and progesterone in …

[HTML][HTML] Congenital adrenal hyperplasia-the main effect of 21-hydroxylase deficiency

B Carvalho, F Carvalho, D Carvalho - 2022 - intechopen.com
Congenital adrenal hyperplasia (CAH) consists of a group of autosomal recessive disorders
resulting from enzymatic defects in steroidogenesis. More than 95% of CAH cases result …

Management of Fully Pubertal Girls With Nonclassical Congenital Adrenal Hyperplasia: Glucocorticoids Versus Oral Contraceptives

L de Vries, M Baum, M Horovitz, M Phillip, G Barash… - Endocrine Practice, 2022 - Elsevier
Objective To compare clinical outcomes of 3 treatment regimens—glucocorticoids (GCs),
oral contraceptives (OCs), or a combination of both—administered to adolescents and …

Caring for Patients With Congenital Adrenal Hyperplasia Throughout the Lifespan

N Zwayne, R Chawla, K van Leeuwen - Obstetrics & Gynecology, 2022 - journals.lww.com
Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder affecting cortisol
and aldosterone biosynthesis, which can lead to virilization in fetuses with a 46, XX …

[PDF][PDF] Manifestations of polycystic ovary syndrome are similar regardless of the degree of menstrual cycle variation

BM Zamila, H Banu, MS Morshed, S Shah… - Int J Hum Health …, 2022 - researchgate.net
Background: Menstrual irregularities may predict over adverse consequences in polycystic
ovary syndrome (PCOS). Objective: To observe the relation of variants of menstrual cycles …

A rare case report about a congenital adrenal hyperplasia by 21-hydroxylase lock in its pure virilizing form discovered in adolescence

A Alla, N Draoui, I Rami, S Rouf, H Saadi… - Annals of Medicine …, 2022 - journals.lww.com
Discussion: The principal aim of the management at adolescent age is to block
hyperandrogenism and to prevent or manage the complications of classic form and its …