Geroscience‐guided repurposing of FDA‐approved drugs to target aging: A proposed process and prioritization

AS Kulkarni, S Aleksic, DM Berger, F Sierra… - Aging …, 2022 - Wiley Online Library
Common chronic diseases represent the greatest driver of rising healthcare costs, as well as
declining function, independence, and quality of life. Geroscience‐guided approaches seek …

[HTML][HTML] Sex difference and benzene exposure: does it matter?

D Poli, P Mozzoni, S Pinelli, D Cavallo… - International Journal of …, 2022 - mdpi.com
Sex-related biological differences might lead to different effects in women and men when
they are exposed to risk factors. A scoping review was carried out to understand if sex could …

[HTML][HTML] Menthol flavor in E-Cigarette vapor modulates social behavior correlated with central and peripheral changes of immunometabolic signalings

Z Xu, Y Tian, AX Li, J Tang, XY Jing, C Deng… - Frontiers in Molecular …, 2022 - frontiersin.org
The use of electronic cigarette (e-cigarette) has been increasing dramatically worldwide.
More than 8,000 flavors of e-cigarettes are currently marketed and menthol is one of the …

[HTML][HTML] Prenatal Pollutant Exposures and Hypothalamic Development: Early Life Disruption of Metabolic Programming

L Koshko, S Scofield, G Mor… - Frontiers in …, 2022 - frontiersin.org
Environmental contaminants in ambient air pollution pose a serious risk to long-term
metabolic health. Strong evidence shows that prenatal exposure to pollutants can …

The association between oil spill cleanup-related total hydrocarbon exposure and diabetes

HV Jardel, LS Engel, KG Lawrence, PA Stewart… - Environmental …, 2022 - Elsevier
Background Although evidence suggests relationships between some crude oil components
and glycemic dysregulation, no studies have examined oil spill-related chemical exposures …