Antimicrobial peptides (AMPs): A promising class of antimicrobial compounds

M Erdem Büyükkiraz, Z Kesmen - Journal of Applied …, 2022 - academic.oup.com
Antimicrobial peptides (AMPs) are compounds, which have inhibitory activity against
microorganisms. In the last decades, AMPs have become powerful alternative agents that …

Antimicrobial peptides and macromolecules for combating microbial infections: from agents to interfaces

L Yu, K Li, J Zhang, H Jin, A Saleem… - ACS Applied Bio …, 2022 - ACS Publications
Bacterial resistance caused by the overuse of antibiotics and the shelter of biofilms has
evolved into a global health crisis, which drives researchers to continuously explore …

Teixobactin kills bacteria by a two-pronged attack on the cell envelope

R Shukla, F Lavore, S Maity, MGN Derks, CR Jones… - Nature, 2022 - nature.com
Antibiotics that use novel mechanisms are needed to combat antimicrobial resistance,–.
Teixobactin represents a new class of antibiotics with a unique chemical scaffold and lack of …

Antimicrobial mechanisms and clinical application prospects of antimicrobial peptides

X Li, S Zuo, B Wang, K Zhang, Y Wang - Molecules, 2022 - mdpi.com
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …

[HTML][HTML] Focus: antimicrobial resistance: antimicrobial peptides therapy: an emerging alternative for treating drug-resistant bacteria

IE Mba, EI Nweze - The Yale journal of biology and medicine, 2022 - ncbi.nlm.nih.gov
Microbial resistance to antibiotics is an ancient and dynamic issue that has brought a
situation reminiscent of the pre-antibiotic era to the limelight. Currently, antibiotic resistance …

Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation

NM Revie, KR Iyer, ME Maxson, J Zhang, S Yan… - Nature …, 2022 - nature.com
Fungal infections cause more than 1.5 million deaths annually. With an increase in immune-
deficient susceptible populations and the emergence of antifungal drug resistance, there is …

An overview of the potentialities of antimicrobial peptides derived from natural sources

I Dini, MG De Biasi, A Mancusi - Antibiotics, 2022 - mdpi.com
Antimicrobial peptides (AMPs) are constituents of the innate immune system in every kind of
living organism. They can act by disrupting the microbial membrane or without affecting …

The role of antimicrobial peptides as antimicrobial and antibiofilm agents in tackling the silent pandemic of antimicrobial resistance

BS Lopes, A Hanafiah, R Nachimuthu, S Muthupandian… - Molecules, 2022 - mdpi.com
Just over a million people died globally in 2019 due to antibiotic resistance caused by
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella …

Human defensin-inspired discovery of peptidomimetic antibiotics

G Luo, J Zhang, HB Wang, YQ Sun… - Proceedings of the …, 2022 - National Acad Sciences
Antibiotics with multiple mechanisms of action and broad-spectrum are urgently required to
combat the growing health threat posed by resistant pathogenic microorganisms. Combining …

[HTML][HTML] Antimicrobial peptides: bringing solution to the rising threats of antimicrobial resistance in livestock

SI Saeed, AE Mergani, E Aklilu… - Frontiers in veterinary …, 2022 - frontiersin.org
Antimicrobial therapy is the most applied method for treating and preventing bacterial
infection in livestock. However, it becomes less effective due to development of the …