BACKGROUND Spermatozoa acquire their motility and fertilizing abilities during their
maturation through the epididymis. This process is controlled by epididymal epithelial cells …

Background: Lifestyle and environmental factors can negatively impact fertility by means of
oxidative stress. In this context, antioxidant supplementation therapy has gained much …

Non-obstructive azoospermia (NOA) is the most severe form of male infertility and typically
incurable. Defining the genetic basis of NOA has proven challenging, and the most …

Since the birth of Louise Brown in 1978 via IVF, reproductive specialists have acquired
enormous knowledge and refined several procedures, which are nowadays applied in …

Background Varicocoele is a common risk factor associated with reduced male fertility
potential. The current understanding of varicocoele pathophysiology does not completely …

Meiosis occurs specifically in germ cells to produce sperm and oocytes that are competent
for sexual reproduction. Multiple factors are required for successful meiotic entry …

Stem and progenitor cells located within stem cell niches maintain the renewal and
regeneration of tissues and organs throughout the life of an adult organism. Stem cell niche …

The aim of the present study was to identify RNA‐based signatures of male infertility by
sperm transcriptome analysis. In this study, deep sequencing analyses of coding (mRNA) …

Circular RNAs (circRNAs) are highly conserved and ubiquitously expressed noncoding
RNAs that participate in multiple reproduction-related diseases. However, the expression …

Raman spectroscopy is a fast-developing, unmarked, non-invasive, non-destructive
technique which allows for real-time scanning and sampling of biological samples in situ …