It has been noticed in recent years that the unfavorable effects of the gut microbiota could
exhaust host vigor and life, yet knowledge and theory are just beginning to be established …

Astrocytes control many processes of the nervous system in health and disease, and
respond to injury quickly. Astrocytes produce neuroprotective factors in the injured brain to …

Blood-brain barrier (BBB) integrity is critical for proper function of the central nervous system
(CNS). Here, we show that the endothelial Unc5B receptor controls BBB integrity by …

The migration of circulating leukocytes into the central nervous system (CNS) is a key driver
of multiple sclerosis (MS) pathogenesis. The monoclonal antibody natalizumab proved that …

Background Neonatal bacterial meningitis is a common neonatal disease with high
morbidity, and can cause serious sequelae when left untreated. Escherichia coli is the …

Schizophrenia (SZ) is a complex neuropsychiatric disorder, affecting 1% of the world
population. Long-standing clinical observations and molecular data have pointed to a …

As we know, with continuous medical progress, the treatment of many diseases can be
conducted via surgery, which often relies on general anaesthesia for its satisfactory …

Dysregulated inflammatory responses and blood–brain barrier (BBB) dysfunction are
recognized as central factors in the development of psychiatric disorders. The present study …

Postoperative neurocognitive disorders are common neurological complications following
surgery that are generally characterized by varying degrees of cognitive impairment …

Inflammation is a biological process that dynamically alters the surrounding
microenvironment, including participating immune cells. As a well‐protected organ …