[HTML][HTML] Racial differences in prostate cancer characteristics and cancer-specific mortality: an overview
N Hinata, M Fujisawa - The world journal of men's health, 2022 - ncbi.nlm.nih.gov
Racial differences of prostate cancer incidence and mortality among Asian, Black, and
Caucasian men have been known, however, comprehensive update of this topic is not yet …
Caucasian men have been known, however, comprehensive update of this topic is not yet …
French AFU Cancer Committee Guidelines-Update 2022-2024: prostate cancer-Diagnosis and management of localised disease
G Ploussard, G Fiard, E Barret, L Brureau… - Progrès en Urologie, 2022 - Elsevier
Objective The objective of the French Urology Association Cancer Committee is to propose
an update of the recommendations for the diagnosis and management of prostate cancer …
an update of the recommendations for the diagnosis and management of prostate cancer …
[HTML][HTML] African-specific molecular taxonomy of prostate cancer
Prostate cancer is characterized by considerable geo-ethnic disparity. African ancestry is a
significant risk factor, with mortality rates across sub-Saharan Africa of 2.7-fold higher than …
significant risk factor, with mortality rates across sub-Saharan Africa of 2.7-fold higher than …
A multi-phenotype analysis reveals 19 susceptibility loci for basal cell carcinoma and 15 for squamous cell carcinoma
Basal cell carcinoma and squamous cell carcinoma are the most common skin cancers, and
have genetic overlap with melanoma, pigmentation traits, autoimmune diseases, and blood …
have genetic overlap with melanoma, pigmentation traits, autoimmune diseases, and blood …
Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa
Background Genome-wide association studies do not always replicate well across
populations, limiting the generalizability of polygenic risk scores (PRS). Despite higher …
populations, limiting the generalizability of polygenic risk scores (PRS). Despite higher …
Polygenic risk for prostate cancer: decreasing relative risk with age but little impact on absolute risk
DJ Schaid, JP Sinnwell, A Batzler… - The American Journal of …, 2022 - cell.com
Polygenic risk scores (PRSs) for a variety of diseases have recently been shown to have
relative risks that depend on age, and genetic relative risks decrease with increasing age. A …
relative risks that depend on age, and genetic relative risks decrease with increasing age. A …
Do sex hormones confound or mediate the effect of chronotype on breast and prostate cancer? A Mendelian randomization study
Morning-preference chronotype has been found to be protective against breast and prostate
cancer. Sex hormones have been implicated in relation to chronotype and the development …
cancer. Sex hormones have been implicated in relation to chronotype and the development …
Comprehensive methylome sequencing reveals prognostic epigenetic biomarkers for prostate cancer mortality
R Pidsley, D Lam, W Qu, TJ Peters… - Clinical and …, 2022 - Wiley Online Library
Background Prostate cancer is a clinically heterogeneous disease with a subset of patients
rapidly progressing to lethal‐metastatic prostate cancer. Current clinicopathological …
rapidly progressing to lethal‐metastatic prostate cancer. Current clinicopathological …
Inherited risk assessment and its clinical utility for predicting prostate cancer from diagnostic prostate biopsies
Background Many studies on prostate cancer (PCa) germline variants have been published
in the last 15 years. This review critically assesses their clinical validity and explores their …
in the last 15 years. This review critically assesses their clinical validity and explores their …
Prostate Cancer transcriptomic regulation by the interplay of germline risk alleles, somatic mutations, and 3D genomic architecture
Prostate cancer is one of the most heritable human cancers. Genome-wide association
studies have identified at least 185 prostate cancer germline risk alleles, most noncoding …
studies have identified at least 185 prostate cancer germline risk alleles, most noncoding …